This is a Validated Antibody Database (VAD) review about human SIRT1, based on 112 published articles (read how Labome selects the articles), using SIRT1 antibody in all methods. It is aimed to help Labome visitors find the most suited SIRT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SIRT1 synonym: SIR2; SIR2L1; SIR2alpha

Knockout validation
Abcam
domestic rabbit monoclonal (E104)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5b
Abcam SIRT1 antibody (Epitomics, 1104) was used in western blot knockout validation on human samples at 1:1000 (fig 5b). Nat Commun (2018) ncbi
Cell Signaling Technology
mouse monoclonal (1F3)
  • western blot knockout validation; human; fig 1
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot knockout validation on human samples (fig 1). Oncotarget (2016) ncbi
Cell Signaling Technology
mouse monoclonal (1F3)
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Cell Signaling Technology SIRT1 antibody (Santa Cruz, 1F3) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Mol Cancer Ther (2015) ncbi
Abcam
mouse monoclonal (19A7AB4)
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig 9
Abcam SIRT1 antibody (Abcam, ab110304) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 9). Biomed Res Int (2022) ncbi
mouse monoclonal (19A7AB4)
  • western blot; mouse; 1:1000; loading ...; fig 8b
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on mouse samples at 1:1000 (fig 8b). Mol Med Rep (2022) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry; human; loading ...; fig 7a
  • western blot; human; loading ...; fig 7c
Abcam SIRT1 antibody (Abcam, ab110304) was used in immunohistochemistry on human samples (fig 7a) and in western blot on human samples (fig 7c). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; 1:5000; loading ...; fig 2d
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples at 1:5000 (fig 2d). Nat Commun (2021) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry; human; 1:30; loading ...; fig 1d
  • western blot; human; 1:2000; loading ...; fig 1b
Abcam SIRT1 antibody (Abcam, ab110304) was used in immunohistochemistry on human samples at 1:30 (fig 1d) and in western blot on human samples at 1:2000 (fig 1b). Oncol Rep (2021) ncbi
mouse monoclonal (19A7AB4)
  • western blot; mouse; loading ...; fig 2a
Abcam SIRT1 antibody (Abeam, abl 10304) was used in western blot on mouse samples (fig 2a). Cell (2021) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; loading ...; fig 5d
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples (fig 5d). Cancer Sci (2021) ncbi
mouse monoclonal (19A7AB4)
  • other; rat; loading ...; fig 3h
  • western blot; rat; loading ...; fig 3c
Abcam SIRT1 antibody (Abcam, ab110304) was used in other on rat samples (fig 3h) and in western blot on rat samples (fig 3c). Aging (Albany NY) (2020) ncbi
mouse monoclonal (19A7AB4)
  • western blot; mouse; 1:500; fig 5c
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on mouse samples at 1:500 (fig 5c). elife (2020) ncbi
domestic rabbit monoclonal (EPR2849Y)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 2e
Abcam SIRT1 antibody (Abcam, ab76039) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 2e). Neurooncol Adv (2020) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 2e
Abcam SIRT1 antibody (Abcam, ab157401) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 2e). Neurooncol Adv (2020) ncbi
mouse monoclonal (19A7AB4)
  • western blot; mouse; loading ...; fig 1e, 4a
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on mouse samples (fig 1e, 4a). Front Physiol (2020) ncbi
mouse monoclonal (19A7AB4)
  • western blot; human; loading ...; fig 2e
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on human samples (fig 2e). EBioMedicine (2020) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; loading ...; fig 5d
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples (fig 5d). elife (2020) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry; mouse; loading ...; fig 4b
  • western blot; mouse; loading ...; fig 4a
  • immunocytochemistry; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 1a
Abcam SIRT1 antibody (Abcam, 110304) was used in immunohistochemistry on mouse samples (fig 4b), in western blot on mouse samples (fig 4a), in immunocytochemistry on human samples (fig 1b) and in western blot on human samples (fig 1a). Int J Chron Obstruct Pulmon Dis (2019) ncbi
mouse monoclonal (19A7AB4)
  • western blot; rat; loading ...; fig 6a
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on rat samples (fig 6a). Braz J Med Biol Res (2019) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; loading ...; fig s1
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples (fig s1). Methods (2019) ncbi
domestic rabbit monoclonal (E104)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5b
Abcam SIRT1 antibody (Epitomics, 1104) was used in western blot knockout validation on human samples at 1:1000 (fig 5b). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • ChIP-Seq; human; 1:100; fig s6c
Abcam SIRT1 antibody (Abcam, Ab12193) was used in ChIP-Seq on human samples at 1:100 (fig s6c). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EPNCIR153)
  • ChIP-Seq; human; loading ...; fig 4c
  • western blot; human; loading ...; fig 2b
In order to research the association between phosphorylated SIRT1 with replication origins and its effect on genomic stability, Abcam SIRT1 antibody (Abcam, ab156585) was used in ChIP-Seq on human samples (fig 4c) and in western blot on human samples (fig 2b). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; 1:1000; loading ...; fig 1d
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples at 1:1000 (fig 1d). Nat Cell Biol (2017) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; loading ...; fig 4f
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples (fig 4f). Cell Death Differ (2017) ncbi
domestic rabbit monoclonal (EP2850Y)
  • western blot; mouse; loading ...; fig 1c
Abcam SIRT1 antibody (Abcam, ab76029) was used in western blot on mouse samples (fig 1c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EPR2849Y)
  • western blot; mouse; loading ...; fig 1c
Abcam SIRT1 antibody (Abcam, ab76039) was used in western blot on mouse samples (fig 1c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human; loading ...; fig 2a
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples (fig 2a). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (E104)
  • western blot; mouse; loading ...; fig 3a
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on mouse samples (fig 3a). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2b
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry - paraffin section on human samples (fig 2a) and in western blot on human samples (fig 2b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry - paraffin section; human; 1:750; fig 2
  • western blot; human; 1:1000; fig 5
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry - paraffin section on human samples at 1:750 (fig 2) and in western blot on human samples at 1:1000 (fig 5). Oncotarget (2016) ncbi
mouse monoclonal (19A7AB4)
  • western blot; mouse; 1:1000; fig 4
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry; human; 1:500; fig 1
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry on human samples at 1:500 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry - paraffin section; human; 1:50
In order to determine the role of Sirt1 in regulating the expression of tissue-restricted antigens in medullary thymic epithelial cells, Abcam SIRT1 antibody (Abcam, 110304) was used in immunohistochemistry - paraffin section on human samples at 1:50. Nat Immunol (2015) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Onco Targets Ther (2015) ncbi
mouse monoclonal (19A7AB4)
  • immunohistochemistry - paraffin section; mouse; 1:200
  • western blot; mouse; 1:1500
In order to investigate the effect of resveratrol on osteoarthritis in mice, Abcam SIRT1 antibody (Abcam, ab110304) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 and in western blot on mouse samples at 1:1500. J Orthop Res (2015) ncbi
domestic rabbit monoclonal (E104)
  • immunoprecipitation; human
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunoprecipitation on human samples . J Steroid Biochem Mol Biol (2015) ncbi
mouse monoclonal (19A7AB4)
  • western blot; rat; 1:2000; loading ...; fig 3a
Abcam SIRT1 antibody (Abcam, ab110304) was used in western blot on rat samples at 1:2000 (fig 3a). PLoS ONE (2014) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry - paraffin section on human samples (fig 1). Histopathology (2015) ncbi
domestic rabbit monoclonal (E104)
  • immunohistochemistry - paraffin section; human
Abcam SIRT1 antibody (Abcam, ab32441) was used in immunohistochemistry - paraffin section on human samples . BMC Cancer (2014) ncbi
domestic rabbit monoclonal (E104)
  • western blot; human
Abcam SIRT1 antibody (Abcam, ab32441) was used in western blot on human samples . FASEB J (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-7)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6h
  • western blot; mouse; loading ...; fig 6f
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in immunohistochemistry on mouse samples at 1:1000 (fig 6h) and in western blot on mouse samples (fig 6f). Aging (Albany NY) (2021) ncbi
mouse monoclonal (B-7)
  • immunohistochemistry; rat; 1:200; loading ...; fig 9
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in immunohistochemistry on rat samples at 1:200 (fig 9). Biomolecules (2020) ncbi
mouse monoclonal (B-7)
  • western blot; rat; loading ...; fig 4c
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in western blot on rat samples (fig 4c). Biosci Rep (2019) ncbi
  • immunoprecipitation; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, H-300) was used in immunoprecipitation on human samples (fig 1a) and in western blot on human samples (fig 2d). J Biol Chem (2019) ncbi
mouse monoclonal (B-10)
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, B-10) was used in western blot on human samples (fig 1a). Nucleic Acids Res (2018) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, B-10) was used in western blot on human samples (fig 1a). Nucleic Acids Res (2018) ncbi
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology SIRT1 antibody (SantaCruz, H-300) was used in western blot on human samples (fig 2a). Mol Psychiatry (2018) ncbi
  • immunocytochemistry; human; 1:2000; loading ...; fig 1e
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, H-300) was used in immunocytochemistry on human samples at 1:2000 (fig 1e). Oncogene (2018) ncbi
  • western blot; mouse; 1:1000; loading ...; fig s2c
Santa Cruz Biotechnology SIRT1 antibody (Santa, H-300) was used in western blot on mouse samples at 1:1000 (fig s2c). Nat Commun (2018) ncbi
  • immunoprecipitation; mouse; loading ...; fig 2c
  • immunohistochemistry; mouse; loading ...; fig 2a
  • western blot; mouse; loading ...; fig 2c
Santa Cruz Biotechnology SIRT1 antibody (Santacruz, sc-15404) was used in immunoprecipitation on mouse samples (fig 2c), in immunohistochemistry on mouse samples (fig 2a) and in western blot on mouse samples (fig 2c). PLoS Pathog (2017) ncbi
  • western blot; mouse; loading ...; fig s4B
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, H-300) was used in western blot on mouse samples (fig s4B). Cell Rep (2017) ncbi
  • western blot; mouse; loading ...; fig 1c
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-15404) was used in western blot on mouse samples (fig 1c). Nat Commun (2016) ncbi
  • immunocytochemistry; human; loading ...; fig s3b
  • western blot; human; loading ...; fig s2f
Santa Cruz Biotechnology SIRT1 antibody (SantaCruz, H-300) was used in immunocytochemistry on human samples (fig s3b) and in western blot on human samples (fig s2f). J Cell Biol (2016) ncbi
mouse monoclonal (11.69)
  • western blot; human; 1:800; loading ...; fig 2
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-135791) was used in western blot on human samples at 1:800 (fig 2). Mol Med Rep (2016) ncbi
mouse monoclonal (33.36)
  • chromatin immunoprecipitation; human; 1:500; loading ...; fig 4
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-135792) was used in chromatin immunoprecipitation on human samples at 1:500 (fig 4). Mol Med Rep (2016) ncbi
  • immunohistochemistry; human; 1:100; fig 2e, 2f
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, H-300) was used in immunohistochemistry on human samples at 1:100 (fig 2e, 2f). Diagn Pathol (2016) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in western blot on human samples at 1:500 (fig 1). Oncol Lett (2016) ncbi
  • western blot; mouse; loading ...; fig 1b
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz Biotechnology, H-300) was used in western blot on mouse samples (fig 1b). Sci Rep (2016) ncbi
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2a
  • immunocytochemistry; mouse; fig 4b
  • western blot; mouse; loading ...; fig 2b
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz Biotechnology, H-300) was used in immunohistochemistry - frozen section on mouse samples (fig 2a), in immunocytochemistry on mouse samples (fig 4b) and in western blot on mouse samples (fig 2b). PLoS Pathog (2016) ncbi
mouse monoclonal (B-10)
  • western blot; human; fig 4
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, 74504) was used in western blot on human samples (fig 4). Am J Cancer Res (2016) ncbi
  • immunocytochemistry; mouse; loading ...; fig 1a
In order to assess the ability of agrimol B to modulate SIRT1 activity and fat metabolism, Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-15404) was used in immunocytochemistry on mouse samples (fig 1a). Biochem Biophys Res Commun (2016) ncbi
mouse monoclonal (B-7)
  • western blot; rat; fig 5
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in western blot on rat samples (fig 5). Int J Med Sci (2016) ncbi
mouse monoclonal (B-10)
  • immunohistochemistry; human; 1:100; fig 1
  • western blot; human; 1:100; fig s1
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74504) was used in immunohistochemistry on human samples at 1:100 (fig 1) and in western blot on human samples at 1:100 (fig s1). PLoS ONE (2016) ncbi
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology SIRT1 antibody (SCBT, H-300) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
  • western blot; mouse; loading ...; fig 2
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, SC15404) was used in western blot on mouse samples (fig 2). Oxid Med Cell Longev (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human; fig 2
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in western blot on human samples (fig 2). Sci Rep (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz, sc-74465) was used in western blot on human samples (fig 5a). J Biol Chem (2015) ncbi
mouse monoclonal (B-10)
  • western blot; human; fig s1b
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz Biotechnology, sc-74504) was used in western blot on human samples (fig s1b). Hum Mol Genet (2015) ncbi
mouse monoclonal (B-10)
  • western blot; rat
Santa Cruz Biotechnology SIRT1 antibody (Santa Cruz Biotechnology, sc-74504) was used in western blot on rat samples . Biochem Biophys Res Commun (2012) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 2
In order to describe a gut microbe-vascular microRNA-Sirtuin1 interaction that leads to regulates endothelial function, Invitrogen SIRT1 antibody (Thermo Scientific, PA5-23-063) was used in immunohistochemistry - paraffin section on mouse samples (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4e
In order to elucidate mechanisms by which miR-132 regulates osteogenic differentiation, Invitrogen SIRT1 antibody (Invitrogen, PA5-17074) was used in western blot on mouse samples at 1:500 (fig 4e). Biochem Biophys Res Commun (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; 1:500; loading ...; fig 4c
  • western blot; human; 1:500; loading ...; fig 4c
In order to investigate the molecular mechanism of Sirt1 in osteogenic differentiation, Invitrogen SIRT1 antibody (Invitrogen, PA5-17074) was used in immunoprecipitation on human samples at 1:500 (fig 4c) and in western blot on human samples at 1:500 (fig 4c). Biochem Biophys Res Commun (2016) ncbi
Active Motif
mouse monoclonal (2G1/F7)
  • western blot; human
Active Motif SIRT1 antibody (Active Motif, 39353) was used in western blot on human samples . Epigenetics (2013) ncbi
Novus Biologicals
mouse monoclonal (1F3)
  • immunohistochemistry; mouse; 1:1000; fig 4
Novus Biologicals SIRT1 antibody (Novus, NBP1-51641) was used in immunohistochemistry on mouse samples at 1:1000 (fig 4). Transl Psychiatry (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C14H4)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2496) was used in western blot on human samples at 1:1000 (fig 4). Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; loading ...; fig 4j
Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 9475S) was used in western blot on mouse samples (fig 4j). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475T) was used in western blot on mouse samples (fig 3a). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology SIRT1 antibody (Cell Signaling, D1D7) was used in western blot on mouse samples (fig 5a). J Clin Invest (2021) ncbi
mouse monoclonal (1F3)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot on mouse samples (fig 4b). Front Physiol (2021) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on mouse samples at 1:1000 (fig 3c). Aging Cell (2021) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; fig 4a
Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 9475S) was used in western blot on mouse samples (fig 4a). Antioxidants (Basel) (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5g
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2493T) was used in western blot on human samples at 1:1000 (fig 5g). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (D1D7)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3b
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 3b). Front Cell Dev Biol (2020) ncbi
mouse monoclonal (1F3)
  • western blot; mouse; 1:500; fig 5h
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot on mouse samples at 1:500 (fig 5h). BMC Biol (2021) ncbi
mouse monoclonal (1F3)
  • immunocytochemistry; human; loading ...
  • western blot; human; loading ...; fig 1a, 1c
Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 8469) was used in immunocytochemistry on human samples and in western blot on human samples (fig 1a, 1c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 3c
Cell Signaling Technology SIRT1 antibody (Cell signal, 2310) was used in western blot on rat samples at 1:1000 (fig 3c). BMC Cardiovasc Disord (2020) ncbi
mouse monoclonal (1F3)
  • western blot; rat; 1:1000; loading ...; fig 4a
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469S) was used in western blot on rat samples at 1:1000 (fig 4a). J Clin Invest (2020) ncbi
domestic rabbit monoclonal (C14H4)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2496) was used in western blot on human samples (fig 2a). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; human; loading ...; fig s2
Cell Signaling Technology SIRT1 antibody (CST, 9475) was used in western blot on human samples (fig s2). Cell Commun Signal (2019) ncbi
mouse monoclonal (1F3)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology SIRT1 antibody (Cell signaling, 1F3) was used in western blot on human samples at 1:1000 (fig 3c). Aging (Albany NY) (2019) ncbi
mouse monoclonal (1F3)
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot on mouse samples at 1:1000 (fig 6e). Nat Commun (2018) ncbi
domestic rabbit monoclonal (C14H4)
  • western blot; human; 1:1000; fig 4e
Cell Signaling Technology SIRT1 antibody (Cell signalling, 2496) was used in western blot on human samples at 1:1000 (fig 4e). Nat Commun (2017) ncbi
mouse monoclonal (1F3)
  • western blot; human; loading ...; fig 3a
In order to determine that SIRT1 is functionally required for sustaining the proliferation and survival of primary effusion lymphoma cells, Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 8469) was used in western blot on human samples (fig 3a). J Pathol (2017) ncbi
mouse monoclonal (1F3)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology SIRT1 antibody (CST, 8469) was used in western blot on human samples (fig 7a). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (C14H4)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology SIRT1 antibody (Cell Signalling, 2496) was used in western blot on human samples (fig 2c). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; rat; 1:1000; loading ...; fig 4a
In order to measure brain insulin signaling in response to dexamethasone treatment in female Charles Foster rats, Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on rat samples at 1:1000 (fig 4a). Mol Neurobiol (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...
  • western blot; human; 1:1000; loading ...
In order to investigate the role of CHCHD2 in the differentiation of human induced pluripotent stem cell, Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2493) was used in immunoprecipitation on human samples and in western blot on human samples at 1:1000. J Cell Biol (2016) ncbi
mouse monoclonal (1F3)
  • western blot; mouse; loading ...; fig 4
In order to evaluate the antifibrotic effect of emodin in silica inhalation-induced lung fibrosis, Cell Signaling Technology SIRT1 antibody (Cell signaling, 8469) was used in western blot on mouse samples (fig 4). Mol Med Rep (2016) ncbi
mouse monoclonal (1F3)
  • western blot knockout validation; human; fig 1
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot knockout validation on human samples (fig 1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 5i
Cell Signaling Technology SIRT1 antibody (Cell Signaling, D1D7) was used in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 5i). Oncogene (2017) ncbi
mouse monoclonal (1F3)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 8469) was used in western blot on human samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (1F3)
  • western blot; human; 1:500; loading ...; fig 2
Cell Signaling Technology SIRT1 antibody (Cell signaling, 8469S) was used in western blot on human samples at 1:500 (fig 2). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; rat; 1:2000; loading ...; fig 5
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on rat samples at 1:2000 (fig 5). Exp Ther Med (2016) ncbi
domestic rabbit monoclonal (C14H4)
  • western blot; human; fig s1
Cell Signaling Technology SIRT1 antibody (Cell Signaling Tech, 2496) was used in western blot on human samples (fig s1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on mouse samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (1F3)
  • western blot; rat; loading ...; fig 3a
In order to investigate the role of autophagy in the anti-neurotoxicity effect of resveratrol, Cell Signaling Technology SIRT1 antibody (Cell signaling, 8469S) was used in western blot on rat samples (fig 3a). Neurochem Res (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; fig 2a
In order to research the effects of environmental tobacco smoke on autophagy and longevity, Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on mouse samples (fig 2a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 8b
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2493) was used in western blot on human samples (fig 8b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 2310) was used in western blot on human samples (fig 2). Cancer Res (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; 1:100; tbl 1
In order to elucidate a deletion of AMP-activated protein kinase in mouse Sertoli cells that modify germ cell quality, Cell Signaling Technology SIRT1 antibody (Cell Signalling, 9475) was used in western blot on mouse samples at 1:100 (tbl 1). Mol Cell Endocrinol (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • immunohistochemistry - paraffin section; mouse; 1:100
  • western blot; mouse; 1:1000
In order to describe a SUMO-specific protease-based methodology suitable for mass spectroscopy, Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 9475P) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 and in western blot on mouse samples at 1:1000. Nat Commun (2015) ncbi
domestic rabbit monoclonal (C14H4)
  • western blot; human; fig 2
Cell Signaling Technology SIRT1 antibody (Cell signaling, 2496) was used in western blot on human samples (fig 2). Am J Physiol Heart Circ Physiol (2015) ncbi
domestic rabbit monoclonal (D1D7)
  • immunohistochemistry - paraffin section; mouse; 1:100
  • western blot; mouse; 1:1000
Cell Signaling Technology SIRT1 antibody (Cell Signaling Technology, 9475) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 and in western blot on mouse samples at 1:1000. Eur J Pharmacol (2015) ncbi
domestic rabbit monoclonal (D1D7)
  • immunohistochemistry - paraffin section; rat; fig 7
  • immunocytochemistry; rat; fig 7
  • western blot; rat; 1:1000; fig 6
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in immunohistochemistry - paraffin section on rat samples (fig 7), in immunocytochemistry on rat samples (fig 7) and in western blot on rat samples at 1:1000 (fig 6). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; human
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475s) was used in western blot on human samples . J Diabetes (2016) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; human
Cell Signaling Technology SIRT1 antibody (Cell Signaling, 9475) was used in western blot on human samples . Biomaterials (2015) ncbi
mouse monoclonal (1F3)
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Cell Signaling Technology SIRT1 antibody (Santa Cruz, 1F3) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Mol Cancer Ther (2015) ncbi
mouse monoclonal (1F3)
  • immunocytochemistry; hamsters; 1:100
  • western blot; hamsters
Cell Signaling Technology SIRT1 antibody (CST, 8469s) was used in immunocytochemistry on hamsters samples at 1:100 and in western blot on hamsters samples . J Mol Neurosci (2015) ncbi
domestic rabbit monoclonal (D1D7)
  • western blot; mouse; fig 1d
  • western blot; human; fig 1c
Cell Signaling Technology SIRT1 antibody (Cell signalling, 9475) was used in western blot on mouse samples (fig 1d) and in western blot on human samples (fig 1c). Am J Cancer Res (2014) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1c
MilliporeSigma SIRT1 antibody (sigma, HPA 006295) was used in western blot on mouse samples (fig 1c). Aging Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig s4b
MilliporeSigma SIRT1 antibody (Sigma-Aldrich, HPA006295) was used in western blot on mouse samples (fig s4b). Cell (2018) ncbi
Articles Reviewed
  1. Zhou Q, Li J, Xiang Z, Zou H, Shao X. Amelioration of Renal Injury by Resveratrol in a Rat Renal Transplantation Model via Activation of the SIRT1/NF-κB Signaling Pathway. Biomed Res Int. 2022;2022:7140961 pubmed publisher
  2. Capitanio D, Moriggi M, Barbacini P, Torretta E, Moroni I, Blasevich F, et al. Molecular Fingerprint of BMD Patients Lacking a Portion in the Rod Domain of Dystrophin. Int J Mol Sci. 2022;23: pubmed publisher
  3. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  4. Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed publisher
  5. Guo W, Liu J, Cheng L, Liu Z, Zheng X, Liang H, et al. Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way. Front Pharmacol. 2021;12:704112 pubmed publisher
  6. Höllmüller E, Geigges S, Niedermeier M, Kammer K, Kienle S, Rösner D, et al. Site-specific ubiquitylation acts as a regulator of linker histone H1. Nat Commun. 2021;12:3497 pubmed publisher
  7. Jiang D, Zhang J, Lin S, Wang Y, Chen Y, Fan J. Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet. Front Cell Dev Biol. 2021;9:628143 pubmed publisher
  8. Kim C, Jin J, Ye Z, Jadhav R, Gustafson C, Hu B, et al. Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021;131: pubmed publisher
  9. Wang X, Lu Y, Tuo Z, Zhou H, Zhang Y, Cao Z, et al. Role of SIRT1/AMPK signaling in the proliferation, migration and invasion of renal cell carcinoma cells. Oncol Rep. 2021;45: pubmed publisher
  10. Dong W, Zhang H, Zhao C, Luo Y, Chen Y. Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway. Front Physiol. 2021;12:624989 pubmed publisher
  11. Shin M, Vázquez Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón Pérez C, et al. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021;184:2715-2732.e23 pubmed publisher
  12. Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed publisher
  13. Swiader A, Camaré C, Guerby P, Salvayre R, Negre Salvayre A. 4-Hydroxynonenal Contributes to Fibroblast Senescence in Skin Photoaging Evoked by UV-A Radiation. Antioxidants (Basel). 2021;10: pubmed publisher
  14. Zheng Z, Yang P, Luo W, Yu S, Xu H, Huang Y, et al. STAT3β Enhances Sensitivity to Concurrent Chemoradiotherapy by Inducing Cellular Necroptosis in Esophageal Squamous Cell Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
  15. Cui H, Yu W, Yu M, Luo Y, Yang M, Cong R, et al. GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression. Cancer Sci. 2021;112:1798-1810 pubmed publisher
  16. Gentile G, Paciello F, Zorzi V, Spampinato A, Guarnaccia M, Crispino G, et al. miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis. Front Cell Dev Biol. 2020;8:616878 pubmed publisher
  17. Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed publisher
  18. Huang S, You S, Qian J, Dai C, Shen S, Wang J, et al. Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling. Aging (Albany NY). 2021;13:4409-4427 pubmed publisher
  19. Meng F, Qian M, Peng B, Peng L, Wang X, Zheng K, et al. Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice. elife. 2020;9: pubmed publisher
  20. Chen J, Zhang M, Zhang S, Wu J, Xue S. Rno-microRNA-30c-5p promotes myocardial ischemia reperfusion injury in rats through activating NF-κB pathway and targeting SIRT1. BMC Cardiovasc Disord. 2020;20:240 pubmed publisher
  21. Qian W, Cai X, Qian Q. Sirt1 antisense long non-coding RNA attenuates pulmonary fibrosis through sirt1-mediated epithelial-mesenchymal transition. Aging (Albany NY). 2020;12:4322-4336 pubmed publisher
  22. Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed publisher
  23. Che H, Li J, Li Y, Ma C, Liu H, Qin J, et al. p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle. elife. 2020;9: pubmed publisher
  24. Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed publisher
  25. Laws M, Bonomi R, Gelovani D, Llaniguez J, Lu X, Mangner T, et al. Noninvasive quantification of SIRT1 expression-activity and pharmacologic inhibition in a rat model of intracerebral glioma using 2-[18F]BzAHA PET/CT/MRI. Neurooncol Adv. 2020;2:vdaa006 pubmed publisher
  26. Li X, Zhu Q, Zheng R, Yan J, Wei M, Fan Y, et al. Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes. Front Physiol. 2020;11:73 pubmed publisher
  27. Xiang Q, Kang L, Wang J, Liao Z, Song Y, Zhao K, et al. CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis. EBioMedicine. 2020;53:102679 pubmed publisher
  28. Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed publisher
  29. Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez Bonet E, Martin Castillo B, et al. Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity. Aging (Albany NY). 2020;12:8-34 pubmed publisher
  30. Zhou H, Zeng H, Yuan D, Ren J, Cheng S, Yu H, et al. NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma. Cell Commun Signal. 2019;17:168 pubmed publisher
  31. Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher
  32. Wang J, Dong Z, Gui M, Yao L, Li J, Zhou X, et al. HuoXue QianYang QuTan Recipe attenuates left ventricular hypertrophy in obese hypertensive rats by improving mitochondrial function through SIRT1/PGC-1α deacetylation pathway. Biosci Rep. 2019;39: pubmed publisher
  33. Lai T, Wen X, Wu D, Su G, Gao Y, Chen C, et al. SIRT1 protects against urban particulate matter-induced airway inflammation. Int J Chron Obstruct Pulmon Dis. 2019;14:1741-1752 pubmed publisher
  34. Zhang X, Qin Q, Dai H, Cai S, Zhou C, Guan J. Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression. Braz J Med Biol Res. 2019;52:e7994 pubmed publisher
  35. Zhang M, Hu C, Moses N, Haakenson J, Xiang S, Quan D, et al. HDAC6 regulates DNA damage response via deacetylating MLH1. J Biol Chem. 2019;294:5813-5826 pubmed publisher
  36. Serebryannyy L, Misteli T. HiPLA: High-throughput imaging proximity ligation assay. Methods. 2019;157:80-87 pubmed publisher
  37. Herskovits A, Hunter T, Maxwell N, Pereira K, Whittaker C, Valdez G, et al. SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. Aging Cell. 2018;17:e12839 pubmed publisher
  38. Liu X, Cai S, Zhang C, Liu Z, Luo J, Xing B, et al. Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Res. 2018;46:9601-9616 pubmed publisher
  39. Hartl D, May P, Gu W, Mayhaus M, Pichler S, Spaniol C, et al. A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. Mol Psychiatry. 2018;: pubmed publisher
  40. Klein M, Dickson M, Antonescu C, Qin L, Dooley S, Barlas A, et al. PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence. Oncogene. 2018;37:5066-5078 pubmed publisher
  41. Li T, Song L, Sun Y, Li J, Yi C, Lam S, et al. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate. Nat Commun. 2018;9:1916 pubmed publisher
  42. Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. Cell. 2018;173:74-89.e20 pubmed publisher
  43. Li F, Liu J, Bao R, Yan G, Feng X, Xu Y, et al. Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nat Commun. 2018;9:508 pubmed publisher
  44. Monteagudo S, Cornelis F, Aznar López C, Yibmantasiri P, Guns L, Carmeliet P, et al. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nat Commun. 2017;8:15889 pubmed publisher
  45. Utani K, Fu H, Jang S, Marks A, Smith O, Zhang Y, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability. Nucleic Acids Res. 2017;45:7807-7824 pubmed publisher
  46. Cha Y, Han M, Cha H, Zoldan J, Burkart A, Jung J, et al. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis. Nat Cell Biol. 2017;19:445-456 pubmed publisher
  47. He M, Tan B, Vasan K, Yuan H, Cheng F, Ramos da Silva S, et al. SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells. J Pathol. 2017;242:309-321 pubmed publisher
  48. Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher
  49. Yuan H, Tan B, Gao S. Tenovin-6 impairs autophagy by inhibiting autophagic flux. Cell Death Dis. 2017;8:e2608 pubmed publisher
  50. Burikhanov R, Hebbar N, Noothi S, Shukla N, Sledziona J, Araujo N, et al. Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis. Cell Rep. 2017;18:508-519 pubmed publisher
  51. Wang Y, Liang H, Zhou G, Hu X, Liu Z, Jin F, et al. HIC1 and miR-23~27~24 clusters form a double-negative feedback loop in breast cancer. Cell Death Differ. 2017;24:421-432 pubmed publisher
  52. Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
  53. Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D Angelo C, et al. SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage. Nucleic Acids Res. 2017;45:1820-1834 pubmed publisher
  54. Bendre S, Rondelet A, Hall C, Schmidt N, Lin Y, Brouhard G, et al. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. J Cell Biol. 2016;215:631-647 pubmed
  55. Chen G, Yu W, Chen X. SirT1 activator represses the transcription of TNF?? in THP?1 cells of a sepsis model via deacetylation of H4K16. Mol Med Rep. 2016;14:5544-5550 pubmed publisher
  56. Shen X, Wang M, Bi X, Zhang J, Wen S, Fu G, et al. Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR??/HO?1 pathways. Mol Med Rep. 2016;14:5528-5534 pubmed publisher
  57. Chruvattil R, Banerjee S, Nath S, Machhi J, Kharkwal G, Yadav M, et al. Dexamethasone Alters the Appetite Regulation via Induction of Hypothalamic Insulin Resistance in Rat Brain. Mol Neurobiol. 2017;54:7483-7496 pubmed publisher
  58. Zhu L, Gómez Durán A, Saretzki G, Jin S, Tilgner K, Melguizo Sanchís D, et al. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J Cell Biol. 2016;215:187-202 pubmed
  59. Wan X, Wen J, Koo S, Liang L, Garg N. SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease. PLoS Pathog. 2016;12:e1005954 pubmed publisher
  60. Yang T, Wang J, Pang Y, Dang X, Ren H, Liu Y, et al. Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact. Mol Med Rep. 2016;14:4643-4649 pubmed publisher
  61. Yu L, Li J, Xu S, Navia Miranda M, Wang G, Duan Y. An Xp11.2 translocation renal cell carcinoma with SMARCB1 (INI1) inactivation in adult end-stage renal disease: a case report. Diagn Pathol. 2016;11:98 pubmed
  62. He M, Yuan H, Tan B, Bai R, Kim H, Bae S, et al. SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. Oncotarget. 2016;7:75698-75711 pubmed publisher
  63. Romeo S, Conti A, Polito F, Tomasello C, Barresi V, La Torre D, et al. miRNA regulation of Sirtuin-1 expression in human astrocytoma. Oncol Lett. 2016;12:2992-2998 pubmed
  64. Haney S, Upchurch G, Opavska J, Klinkebiel D, Appiah A, Smith L, et al. Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice. Sci Rep. 2016;6:34222 pubmed publisher
  65. Li Z, Bridges B, Olson J, Weinman S. The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3. Oncogene. 2017;36:1887-1898 pubmed publisher
  66. Maroui M, Callé A, Cohen C, Streichenberger N, Texier P, Takissian J, et al. Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment. PLoS Pathog. 2016;12:e1005834 pubmed publisher
  67. Vikram A, Kim Y, Kumar S, Li Q, Kassan M, JACOBS J, et al. Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1. Nat Commun. 2016;7:12565 pubmed publisher
  68. Timucin A, Basaga H. SIRT6 Is a Positive Regulator of Aldose Reductase Expression in U937 and HeLa cells under Osmotic Stress: In Vitro and In Silico Insights. PLoS ONE. 2016;11:e0161494 pubmed publisher
  69. Wawrzyniak N, Joseph A, Levin D, Gundermann D, Leeuwenburgh C, Sandesara B, et al. Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle. Oncotarget. 2016;7:52695-52709 pubmed publisher
  70. Liu M, Shan J, Li J, Zhang Y, Lin X. Resveratrol inhibits doxorubicin-induced cardiotoxicity via sirtuin 1 activation in H9c2 cardiomyocytes. Exp Ther Med. 2016;12:1113-1118 pubmed
  71. Liu X, Ehmed E, Li B, Dou J, Qiao X, Jiang W, et al. Breast cancer metastasis suppressor 1 modulates SIRT1-dependent p53 deacetylation through interacting with DBC1. Am J Cancer Res. 2016;6:1441-9 pubmed
  72. Gong K, Qu B, Liao D, Liu D, Wang C, Zhou J, et al. MiR-132 regulates osteogenic differentiation via downregulating Sirtuin1 in a peroxisome proliferator-activated receptor ?/?-dependent manner. Biochem Biophys Res Commun. 2016;478:260-267 pubmed publisher
  73. Qu B, Ma Y, Yan M, Gong K, Liang F, Deng S, et al. Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor ? in MC3T3-E1 cells. Biochem Biophys Res Commun. 2016;478:439-445 pubmed publisher
  74. Tsai S, Huang P, Hsu Y, Peng Y, Lee C, Wang J, et al. Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep. 2016;6:28612 pubmed publisher
  75. Wang S, Zhang Q, Zhang Y, Shen C, Wang Z, Wu Q, et al. Agrimol B suppresses adipogenesis through modulation of SIRT1-PPAR gamma signal pathway. Biochem Biophys Res Commun. 2016;477:454-60 pubmed publisher
  76. Wang K, Cao P, Wang H, Tang Z, Wang N, Wang J, et al. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep. 2016;6:26229 pubmed publisher
  77. Deng H, Mi M. Resveratrol Attenuates A?25-35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway. Neurochem Res. 2016;41:2367-79 pubmed publisher
  78. Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher
  79. Huang C, Wang T, Tung Y, Lin W. Effect of Exercise Training on Skeletal Muscle SIRT1 and PGC-1? Expression Levels in Rats of Different Age. Int J Med Sci. 2016;13:260-70 pubmed publisher
  80. Kumar P, Sharad S, Petrovics G, Mohamed A, Dobi A, Sreenath T, et al. Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1. Oncotarget. 2016;7:22791-806 pubmed publisher
  81. Tobita T, Guzman Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, et al. SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 2016;11:e0149344 pubmed publisher
  82. Perumal D, Kuo P, Leshchenko V, Jiang Z, Divakar S, Cho H, et al. Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma. Cancer Res. 2016;76:1225-36 pubmed publisher
  83. Wang Y, Cui R, Zhang X, Qiao Y, Liu X, Chang Y, et al. SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma. Oncotarget. 2016;7:11284-98 pubmed publisher
  84. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  85. Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  86. Bartosch C, Monteiro Reis S, Almeida Rios D, Vieira R, Castro A, Moutinho M, et al. Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium. Oncotarget. 2016;7:1144-54 pubmed publisher
  87. Tuon T, Souza P, Santos M, Pereira F, Pedroso G, Luciano T, et al. Physical Training Regulates Mitochondrial Parameters and Neuroinflammatory Mechanisms in an Experimental Model of Parkinson's Disease. Oxid Med Cell Longev. 2015;2015:261809 pubmed publisher
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  89. Lo Iacono L, Visco Comandini F, Valzania A, Viscomi M, Coviello M, Giampà A, et al. Adversity in childhood and depression: linked through SIRT1. Transl Psychiatry. 2015;5:e629 pubmed publisher
  90. McGlynn L, McCluney S, Jamieson N, Thomson J, MacDonald A, Oien K, et al. SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients. PLoS ONE. 2015;10:e0131344 pubmed publisher
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  93. Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed publisher
  94. Huang Z, Han Z, Ye B, Dai Z, Shan P, Lu Z, et al. Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes. Eur J Pharmacol. 2015;762:1-10 pubmed publisher
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