This is a Validated Antibody Database (VAD) review about human SOCS1, based on 14 published articles (read how Labome selects the articles), using SOCS1 antibody in all methods. It is aimed to help Labome visitors find the most suited SOCS1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SOCS1 synonym: CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3; suppressor of cytokine signaling 1; JAK binding protein; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Tec-interacting protein 3; cytokine-inducible SH2 protein 1

Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; tbl 1
  • western blot; human; 1:250; fig 5
In order to examine the oncogenic function of signal transducer and activator of transcription 1 in malignant pleural mesothelioma, Invitrogen SOCS1 antibody (Invitrogen, 38-5200) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1) and in western blot on human samples at 1:250 (fig 5). Pathol Oncol Res (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to demonstrate that vitamin D receptor signaling attenuates TLR-mediated inflammation, Invitrogen SOCS1 antibody (Zymed laboratories, 38-5200) was used in western blot on human samples (fig 6). J Immunol (2013) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3f
Abcam SOCS1 antibody (Abcam, ab62584) was used in western blot on human samples at 1:1000 (fig 3f). Nat Microbiol (2018) ncbi
MilliporeSigma
rabbit polyclonal
  • immunocytochemistry; chicken; loading ...; fig 3
  • western blot; chicken; loading ...; fig 3
MilliporeSigma SOCS1 antibody (Sigma, av42147) was used in immunocytochemistry on chicken samples (fig 3) and in western blot on chicken samples (fig 3). Dev Comp Immunol (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology SOCS1 antibody (Cell Signaling, 3950s) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4b
In order to investigate the oncogenic effect of miR-210-3p in prostate cancer and bone metastasis and its mechanism, Cell Signaling Technology SOCS1 antibody (cell signalling, 3950) was used in western blot on human samples (fig 4b). Mol Cancer (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology SOCS1 antibody (Cell signaling, 3950) was used in western blot on mouse samples (fig 5a). Mol Biol Cell (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
In order to show that the MEK1/2 pathway is a key regulator of macrophage reparative properties, Cell Signaling Technology SOCS1 antibody (Cell Signaling, 3950) was used in western blot on mouse samples (fig 3a). J Immunol (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to investigate the effect of a microtubule inhibitor, MPT0B098, on STAT3 signaling in oral squamous cell carcinoma, Cell Signaling Technology SOCS1 antibody (Cell Signaling, 3950) was used in western blot on human samples (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 9
  • western blot; human; 1:1000; fig 4
In order to investigate if microRNAs contribute to macrophage's fibrogenesis, Cell Signaling Technology SOCS1 antibody (Cell Signaling Technology, 3950) was used in western blot on mouse samples at 1:1000 (fig 9) and in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology SOCS1 antibody (Cell signaling, 3950) was used in western blot on human samples (fig 5). BMC Genomics (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology SOCS1 antibody (Cell Signaling, A156) was used in western blot on human samples (fig 1c). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:300
Cell Signaling Technology SOCS1 antibody (Cell Signaling Technology, 3950) was used in western blot on human samples at 1:300. Cell Death Dis (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology SOCS1 antibody (Cell Signaling Technologies, 3950) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
  2. Chen J, Yang Y, Yang Y, Zou P, Chen J, He Y, et al. AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling. Nat Microbiol. 2018;3:302-309 pubmed publisher
  3. Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, et al. Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-?B signaling pathway. Mol Cancer. 2017;16:117 pubmed publisher
  4. Truong A, Hong Y, Hoang C, Lee J, Hong Y. Chicken IL-26 regulates immune responses through the JAK/STAT and NF-κB signaling pathways. Dev Comp Immunol. 2017;73:10-20 pubmed publisher
  5. Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
  6. Long M, Eddy W, Gong K, Lovelace Macon L, McMahan R, Charron J, et al. MEK1/2 Inhibition Promotes Macrophage Reparative Properties. J Immunol. 2017;198:862-872 pubmed publisher
  7. Arzt L, Halbwedl I, Gogg Kamerer M, Popper H. Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma. Pathol Oncol Res. 2017;23:595-605 pubmed publisher
  8. Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher
  9. Su S, Zhao Q, He C, Huang D, Liu J, Chen F, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523 pubmed publisher
  10. Masotti A, Donninelli G, Da Sacco L, Varano B, Del Cornò M, Gessani S. HIV-1 gp120 influences the expression of microRNAs in human monocyte-derived dendritic cells via STAT3 activation. BMC Genomics. 2015;16:480 pubmed publisher
  11. Sukegawa S, Sakuma R, Ohmine S, Takeuchi H, Ikeda Y, Yamaoka S. Suppressor of cytokine signaling 1 counteracts rhesus macaque TRIM5α-induced inhibition of human immunodeficiency virus type-1 production. PLoS ONE. 2014;9:e109640 pubmed publisher
  12. Mathieu M, Miles A, Ahmad M, Buczek M, Pockley A, Rees R, et al. The helicase HAGE prevents interferon-?-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1. Cell Death Dis. 2014;5:e1061 pubmed publisher
  13. Sriram U, Xu J, Chain R, Varghese L, Chakhtoura M, Bennett H, et al. IL-4 suppresses the responses to TLR7 and TLR9 stimulation and increases the permissiveness to retroviral infection of murine conventional dendritic cells. PLoS ONE. 2014;9:e87668 pubmed publisher
  14. Chen Y, Liu W, Sun T, Huang Y, Wang Y, Deb D, et al. 1,25-Dihydroxyvitamin D promotes negative feedback regulation of TLR signaling via targeting microRNA-155-SOCS1 in macrophages. J Immunol. 2013;190:3687-95 pubmed publisher