This is a Validated Antibody Database (VAD) review about human APP, based on 406 published articles (read how Labome selects the articles), using APP antibody in all methods. It is aimed to help Labome visitors find the most suited APP antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
APP synonym: AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4
Knockout validation
Invitrogen domestic rabbit polyclonal (CT695) |
| Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot knockout validation on mouse samples at 1:250 (fig s1). Aging (Albany NY) (2021) ncbi |
Abcam domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Epitomics, ab32136) was used in immunohistochemistry knockout validation on mouse samples (fig 1e), in western blot knockout validation on mouse samples (fig 2) and in immunohistochemistry - free floating section on mouse samples (fig 1d). Front Mol Neurosci (2016) ncbi |
BioLegend
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803015) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4e). Ann Neurol (2021) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 800701) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig s6b). Signal Transduct Target Ther (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320) was used in immunohistochemistry on mouse samples (fig 6a). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803002) was used in immunohistochemistry on mouse samples at 1:100 (fig 6c). Protein Cell (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in western blot on mouse samples at 1:500. Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry on rat samples (fig 1c). Aging (Albany NY) (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803015) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 1a). Aging Cell (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in western blot on rat samples at 1:1000 (fig 2b). Cell Rep (2021) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Biolegend, 800701) was used in immunohistochemistry - paraffin section on African green monkey samples at 1:200 (fig 1g). Protein Cell (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in ELISA on mouse samples . Alzheimers Res Ther (2021) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 800720) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 5g). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803001) was used in immunohistochemistry on human samples at 1:500 (fig 2a). Nat Immunol (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803002) was used in immunohistochemistry on human samples (fig 1a). Front Aging Neurosci (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803004) was used in immunohistochemistry on mouse samples (fig 8). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry on mouse samples at 1:500 (fig 4d). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 6E10) was used in western blot on mouse samples at 1:1000 (fig 1h). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803015) was used in immunohistochemistry on human samples at 1:1000 (fig 1a). Sci Adv (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on mouse samples at 1:100. Int J Mol Sci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry on mouse samples at 1:1000. Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Biolegend, 4G8) was used in immunohistochemistry on mouse samples at 1:500 (fig s2c, s2d). Front Pharmacol (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803001) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 8a) and in immunohistochemistry on mouse samples at 1:200 (fig 3e, 6b). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803002) was used in immunohistochemistry - frozen section on human samples at 1:250 (fig 1b). Acta Neuropathol (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 5c). elife (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples (fig 1b). iScience (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 6E10) was used in immunohistochemistry on mouse samples at 1:400 (fig 2a). Oxid Med Cell Longev (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 4G8) was used in immunohistochemistry on human samples at 1:5000 (tbl 1). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Biolegend, 4G8) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 2a). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet Laboratories, 6E10) was used in other on rat samples (fig 1). Biomolecules (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - paraffin section on human samples (fig 7a) and in immunohistochemistry - paraffin section on mouse samples (fig 6a). Int J Mol Sci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4h). Aging Cell (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 6E10) was used in immunohistochemistry - free floating section on mouse samples at 1:2000 (fig 3a). Mol Ther Nucleic Acids (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803002) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 4a). J Neuroinflammation (2020) ncbi |
mouse monoclonal (11A50-B10) |
| BioLegend APP antibody (Biolegend, 805401) was used in immunohistochemistry on human samples at 1:200 (fig 1b). Acta Neuropathol (2020) ncbi |
mouse monoclonal (M3.2) |
| BioLegend APP antibody (BioLegend, 805701) was used in western blot on rat samples at 1:1000 (fig 2b). elife (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in western blot on rat samples at 1:1000 (fig 2c). elife (2020) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (BioLegend, 802801) was used in proximity ligation assay on rat samples at 1:1000 (fig 2a). BMC Neurosci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803002) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2a) and in western blot on mouse samples at 1:2000 (fig ev4a). EMBO Rep (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 4G8) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1a). Int J Mol Sci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 6E10) was used in western blot on mouse samples at 1:1000 (fig 3a). Int J Mol Sci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in other on mouse samples at 1:2000. J Neurosci (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803001) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 1). Int J Mol Sci (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, SIG-39220) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig s6e). Nat Commun (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 2c, 2d), in western blot on mouse samples (fig 2h), in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 2a, 2b) and in western blot on human samples (fig 2g). Nat Commun (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - paraffin section on mouse samples (fig 3c). Mol Neurodegener (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803001) was used in immunohistochemistry on mouse samples at 1:300 (fig 5a). Nat Commun (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3s1) and in western blot on mouse samples at 1:1000 (fig 6e). Mol Neurodegener (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803003) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2a). Mol Neurodegener (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - free floating section on human samples at 1:5000. J Neuropathol Exp Neurol (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Biolegend (previously Covance), SIG-39220) was used in immunohistochemistry - free floating section on mouse samples at 1:2000 (fig s8g). PLoS Biol (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Biolegend, 4G8) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1b). Acta Neuropathol (2020) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, SIG-39220) was used in immunohistochemistry - frozen section on fruit fly |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry - paraffin section on human samples at 1:4000 (fig 2b). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 800702) was used in immunohistochemistry - paraffin section on human samples at 1:4000 (fig 2b). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 803001) was used in immunohistochemistry - frozen section on human samples at 1:2000 (fig 7b). elife (2019) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:9000 (tbl 2). Neurology (2020) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 6E10) was used in immunohistochemistry on mouse samples at 1:500 (fig s1). Alzheimers Res Ther (2019) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, 800712) was used in immunohistochemistry on mouse samples (fig 5g). Cell Rep (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - paraffin section on human samples at 1:2500 (fig 4a). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig 1a). Nat Neurosci (2019) ncbi |
mouse monoclonal (12F4) |
| BioLegend APP antibody (Biolegend, 805501) was used in immunohistochemistry - free floating section on mouse samples (fig 3g). Cell (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in western blot on mouse samples (fig 3c). Sci Adv (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet Laboratories, 6E10) was used in immunoprecipitation on human samples (fig 1b). J Biol Chem (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320) was used in western blot on mouse samples at 1:11,000 (fig 3b). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 4f). Crit Care (2019) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (BioLegend, SIG-39200) was used in immunohistochemistry on human samples at 1:500 (fig 2e). Sci Adv (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Millipore, SIG-39320) was used in immunohistochemistry on mouse samples at 1:500 (fig 1b). J Comp Neurol (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegend, 6E10) was used in immunohistochemistry - frozen section on mouse samples (fig 2f). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:300 (fig 2d). Nat Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3c). J Clin Invest (2019) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (BioLegend, 802801) was used in western blot on mouse samples at 1:1000 (fig 3h). EMBO Mol Med (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320-1000) was used in western blot on mouse samples at 1:10,000 (fig 3h). EMBO Mol Med (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in western blot on human samples (fig s3g). Nat Commun (2019) ncbi |
mouse monoclonal (M3.2) |
| BioLegend APP antibody (BioLegend, 805701) was used in western blot on mouse samples (fig s2c). Nat Commun (2019) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6e10) was used in flow cytometry on mouse samples (fig 3b) and in immunohistochemistry on mouse samples (fig 3b). Front Cell Neurosci (2018) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (Biolegend, 802801) was used in western blot on human samples at 1:1000 (fig s1b). Science (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance Research Products Inc, 6E10) was used in immunohistochemistry - frozen section on mouse samples (fig 2e). Neurobiol Aging (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples (fig 3a). Mol Psychiatry (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - free floating section on mouse samples (fig 1a). Aging Cell (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 6c) and in western blot on mouse samples at 1:1000 (fig 8b). Autophagy (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples (fig 3b). Acta Neuropathol Commun (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320-1000) was used in western blot on mouse samples at (fig 6t). J Exp Med (2018) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (BioLegend, 802801) was used in western blot on mouse samples at 1:1000 (fig 6t). J Exp Med (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:1000 (fig s1). Nature (2018) ncbi |
domestic rabbit polyclonal (Poly8134) |
| BioLegend APP antibody (Covance, SIG-39138) was used in western blot on human samples (fig 1r). Nat Med (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in western blot on mouse samples at 1:5000 (fig 1b). J Exp Med (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunocytochemistry on mouse samples (fig 3a). J Neuroinflammation (2018) ncbi |
mouse monoclonal (11A50-B10) |
| BioLegend APP antibody (BioLegend, 805407) was used in ELISA on mouse samples (fig 3d). J Neuroinflammation (2018) ncbi |
mouse monoclonal (12F4) |
| BioLegend APP antibody (BioLegend, 805507) was used in ELISA on mouse samples (fig 3d). J Neuroinflammation (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet, SIG-39330-200) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 5a) and in western blot on mouse samples at 1:2000 (fig 4a). J Exp Med (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803002) was used in immunohistochemistry on mouse samples (fig s6b). Proc Natl Acad Sci U S A (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples (fig 1a). Cell Mol Life Sci (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, SIG-39320) was used in immunohistochemistry - frozen section on African green monkey samples at 1:12,000 (fig 4a). Neurobiol Aging (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in western blot on mouse samples at 1:2500 (fig 5a). Am J Pathol (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - frozen section on mouse samples at 1:3000 (fig 1a). EMBO J (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples (fig 2a). Oncotarget (2017) ncbi |
domestic rabbit polyclonal (Poly8134) |
| BioLegend APP antibody (Covance, SIG-39138) was used in western blot on human samples (fig 8a). Exp Neurol (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39347) was used in immunohistochemistry - free floating section on human samples (fig 4d). Exp Neurol (2018) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunocytochemistry on rat samples at 1:1000 (fig 7a). Proc Natl Acad Sci U S A (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - frozen section on African green monkey samples at 1:7500 (fig 1a). Neurobiol Aging (2017) ncbi |
mouse monoclonal (6E10) |
| In order to study the involvement of deacetylase HDAC6 in Tau pathology, BioLegend APP antibody (BioLegend, SIG-39320) was used in immunocytochemistry on human samples at 1:1000 (fig 6a) and in western blot on human samples (fig s1a). Cell Rep (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 803001) was used in immunocytochemistry on mouse samples (fig s5b). PLoS Genet (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples (fig 4d). Proc Natl Acad Sci U S A (2017) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the accumulation of TMEM230 in granulovacuolar degeneration bodies and dystrophic neurites of Alzheimers disease, BioLegend APP antibody (BioLegend, SIG-39320-200) was used in immunohistochemistry - paraffin section on human samples (fig 2a). J Alzheimers Dis (2017) ncbi |
mouse monoclonal (4G8) |
| In order to show that ALOX5 upregulation results in homocysteine-dependent worsening of the Alzheimer's disease phenotype, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry on mouse samples (fig 3c). Sci Rep (2017) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG39220) was used in immunocytochemistry on rat samples (fig s4b). Front Cell Neurosci (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (BioLegend, 6E10) was used in western blot on human samples at 1:2000 (fig 4a). PLoS ONE (2017) ncbi |
mouse monoclonal (6E10) |
| In order to examine tau distribution and release using organotypic brain slice cultures, BioLegend APP antibody (Covance Research Products, SIG-39300-200) was used in western blot on mouse samples (fig 2a). Cell Death Dis (2017) ncbi |
mouse monoclonal (12F4) |
| In order to characterize physiological conformations of Abeta and amyloid precursor protein, BioLegend APP antibody (BioLegend, SIG-39142) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 5a) and in western blot on mouse samples at 1:1000. Nat Commun (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet Laboratories, SIG-39320) was used in immunohistochemistry - free floating section on mouse samples (fig 4j). Front Neurosci (2017) ncbi |
mouse monoclonal (6E10) |
| In order to purify peripheral plasma exosomes and observe exosome diffusion in the hippocampus of an Alzheimer's disease mouse model, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on human samples at 1:1000 (fig 5a). Front Aging Neurosci (2017) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (Biolegend, 802801) was used in proximity ligation assay on rat samples (fig 5D). Front Mol Neurosci (2017) ncbi |
mouse monoclonal (6E10) |
| In order to assess the effects of choline using a mouse model of Alzheimer's disease, BioLegend APP antibody (BioLegend, SIG-39320) was used in western blot on mouse samples at 1:1000 (fig 1e). PLoS ONE (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39300) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig s2a). Stem Cell Reports (2017) ncbi |
mouse monoclonal (4G8) |
| In order to design a quantitative 3D in silico modeling platform allowing for true 3D quantitation of amyloid-beta phagocytosis by mononuclear phagocytes in rodent Alzheimer's Disease models, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1a). J Vis Exp (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Biolegends, SIG-39320) was used in immunocytochemistry on human samples at 1:100 (fig 5b). Acta Neuropathol (2017) ncbi |
mouse monoclonal (6E10) |
| In order to describe a dichotomy between graft structure and clinical function in a patient dying 16 years following fetal nigral grafting, BioLegend APP antibody (Covance, SIG-39300) was used in immunohistochemistry on human samples at 1:2000 (tbl 1). Ann Neurol (2017) ncbi |
mouse monoclonal (6E10) |
| In order to study the role of the STIM2-regulated TRPC6/Orai2 nSOC channel complex in dendritic mushroom spines in models of Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39300) was used in western blot on mouse samples at 1:1000. J Neurosci (2016) ncbi |
mouse monoclonal (6E10) |
| In order to explore the role of necrostatin-1 in Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 1d) and in western blot on mouse samples at 1:1000 (fig 1f). EMBO Mol Med (2017) ncbi |
mouse monoclonal (4G8) |
| In order to evaluate chronic traumatic encephalopathy-like changes during routine neuropathology services, BioLegend APP antibody (BioLegend, SIG39220-500) was used in immunohistochemistry - paraffin section on human samples at 1:4000 (fig 6). J Neuropathol Exp Neurol (2016) ncbi |
mouse monoclonal (6E10) |
| In order to suggest that loss of the Wnt signaling pathway may contribute to Alzheimer's disease pathogenesis, BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples (fig 3b). J Neurochem (2016) ncbi |
mouse monoclonal (6E10) |
| In order to characterize an Alzheimer's disease model that utilizes Octodon degus, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 3). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (4G8) |
| In order to characterize an Alzheimer's disease model that utilizes Octodon degus, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - paraffin section on rat samples at 1:2000 (fig 3). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples (fig 4). Sci Rep (2016) ncbi |
mouse monoclonal (4G8) |
| In order to test if the leptomeningeal arteries derived from patients with cerebral amyloid angiopathy have a distinct endophenotypic profile compared to those from young and elderly controls, BioLegend APP antibody (BioLegend, 800701) was used in immunohistochemistry on human samples at 1:100 (fig 4d). Neuropathol Appl Neurobiol (2017) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples (fig 1b). J Neurosci (2016) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 3b). J Neurosci (2016) ncbi |
mouse monoclonal (6E10) | In order to describe the role of miR-132 in amyloid and TAU pathology associated with Alzheimer's disease, BioLegend APP antibody (BioLegend, 803002) was used . EMBO Mol Med (2016) ncbi | |
domestic rabbit polyclonal (Poly8134) | In order to describe the role of miR-132 in amyloid and TAU pathology associated with Alzheimer's disease, BioLegend APP antibody (Covance BioLegend, 813401) was used . EMBO Mol Med (2016) ncbi | |
mouse monoclonal (4G8) |
| In order to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease, BioLegend APP antibody (Covance, SIG-39220-200) was used in immunohistochemistry - free floating section on human samples at 1:1000 (fig 7c), in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 7c), in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 3b), in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 3b) and in western blot on mouse samples at 1:2000 (fig st7). Autophagy (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, Sig-39340-200) was used in western blot on fruit fly |
mouse monoclonal (6E10) |
| In order to elucidate the pathological conversion of tau facilitated by the neuritic plaque in an Alzheimer's disease mouse model, BioLegend APP antibody (Covance, SIG-39300) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4). Nat Commun (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:2000 (fig 2). Sci Rep (2016) ncbi |
mouse monoclonal (4G8) |
| In order to study the human brain after blast exposure in post-mortem cases to characterize the interface astroglial scarring, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 2). Lancet Neurol (2016) ncbi |
mouse monoclonal (4G8) |
| In order to determine protection against microbial infection in mouse and worm models of Alzheimer's disease by the amyloid-beta peptide, BioLegend APP antibody (Covance, 4G8) was used in blocking or activating experiments on human samples (fig 3) and in immunohistochemistry on human samples (fig 2). Sci Transl Med (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (covance, SIG39320) was used in western blot on human samples (fig 1). Protein Cell (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39300) was used in western blot on mouse samples (fig s1). Sci Rep (2016) ncbi |
mouse monoclonal (12F4) | In order to study a novel platform based on the planar frequency mixing magnetic technique that is a magnetic immunoassay, BioLegend APP antibody (Covance, SIG-39144) was used . Biosens Bioelectron (2016) ncbi | |
mouse monoclonal (6E10) |
| BioLegend APP antibody (covance, SIG-39320-200) was used in immunohistochemistry on mouse samples at 1:100 (fig 3) and in western blot on mouse samples at 1:1000 (fig 3). J Neuroinflammation (2016) ncbi |
mouse monoclonal (6E10) | In order to study behavioral deficits without pathological interaction by humanized tau mice with regionalized amyloid, BioLegend APP antibody (BioLegend, 803015) was used . PLoS ONE (2016) ncbi | |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39300) was used in western blot on human samples (fig 2). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (6E10) |
| In order to study the augmentation of AD-related phosphorylation and A-beta42-induced tau toxicity created by stabilization of microtubule-unbound tau via tau phosphorylation at Ser262/356 by Par-1/MARK, BioLegend APP antibody (Covance, 6E10) was used in western blot on fruit fly |
domestic rabbit polyclonal (Poly8134) |
| In order to characterize epigenetic changes in 5XFAD mice, BioLegend APP antibody (Covance, SIG-39138-050) was used in western blot on mouse samples at 1:1000 (fig 4d). Aging (Albany NY) (2016) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG?\39220) was used in immunoprecipitation on human samples at 1:500-1:2500 (fig 1H). EMBO Mol Med (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (803016, 803016) was used in western blot on mouse samples at 1:5000 (fig 7a). Autophagy (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunoprecipitation on human samples (fig 4). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunoprecipitation on human samples (fig 4). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (6E10) |
| In order to characterize the frontal cortex of wild mountain gorillas (Gorilla beringei beringei) for early Alzheimer's disease-type pathology, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - free floating section on human samples at 1:1000 (tbl 2). Neurobiol Aging (2016) ncbi |
mouse monoclonal (6E10) |
| In order to assess rescue of Alzheimer's disease in the mouse by improved proteostasis in the secretory pathway, BioLegend APP antibody (Signet, 6E10) was used in immunohistochemistry on mouse samples at 1:100 (fig 4) and in western blot on mouse samples at 1:1000 (fig 4). Brain (2016) ncbi |
mouse monoclonal (6E10) |
| In order to study reduction of hyperphosphorilated Tau by beta-secretase 1's targeting implying autophagy actors in 3xTg-AD mice, BioLegend APP antibody (Signet, 6E10) was used in western blot on human samples at 1:1000 (tbl 1) and in western blot on mouse samples at 1:1000 (tbl 1). Front Cell Neurosci (2015) ncbi |
mouse monoclonal (4G8) | BioLegend APP antibody (BioLegend, 800702) was used . J Neurosci (2016) ncbi | |
mouse monoclonal (6E10) |
| In order to identify and characterize a multiprotease complex containing both alpha- and gamma-secretase, BioLegend APP antibody (Covance, 6E10) was used in western blot on hamsters samples (fig 7). J Cell Biol (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on fruit fly |
mouse monoclonal (4G8) |
| In order to assess the impairment in synaptic plasticity and learning due to amyloid-beta dimers in the absence of plaque pathology, BioLegend APP antibody (Covance, 4G8) was used in ELISA on mouse samples at 1:2500 (fig 2) and in western blot on mouse samples (fig 1). Brain (2016) ncbi |
mouse monoclonal (4G8) |
| In order to study Alzheimer's-like neurodegeneration by L-methionine by looking at changes in A-beta oligomers, synaptic proteins, Wnt signaling, tau phosphorylation, and behavioral impairment in wild-type mice, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on mouse samples (fig 2i) and in western blot on mouse samples (fig 2f). Mol Neurodegener (2015) ncbi |
mouse monoclonal (6E10) |
| In order to characterize the interaction of TRPC6 with APP to inhibit its cleavage by gamma-secretase and reduce A-beta production, BioLegend APP antibody (Signet, SIG-39300) was used in immunohistochemistry on mouse samples (fig 5). Nat Commun (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (covance, SIG 39320-200) was used in western blot on mouse samples (fig s5). Front Cell Neurosci (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:1500 (fig 3) and in western blot on human samples at 1:1500 (fig 3). Acta Neuropathol Commun (2015) ncbi |
domestic rabbit monoclonal (1-11-3) |
| BioLegend APP antibody (Covance, 1-11-3) was used in ELISA on human samples (fig s8) and in ELISA on mouse samples (fig s8). Acta Neuropathol Commun (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:250 (fig 5) and in immunohistochemistry on mouse samples at 1:250 (fig 5). Acta Neuropathol Commun (2015) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the contribution of TRPM2 to beta-amyloid neuronal toxicity, BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:2000 (fig 5e). J Neurosci (2015) ncbi |
mouse monoclonal (6E10) |
| In order to characterize linalool that reverses behavioral and neuropathological impairments in old triple transgenic Alzheimer's mice, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:500 (fig 4). Neuropharmacology (2016) ncbi |
mouse monoclonal (6E10) |
| In order to assess microglia phenotypes during chronic neuroinflammation, BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). J Neuroinflammation (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples at 1:1000. Brain (2016) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the pathophysiology of the hypoperfusion in Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in ELISA on human samples at 2 ug/ml (fig 6). Brain Pathol (2016) ncbi |
mouse monoclonal (11A50-B10) |
| In order to investigate the pathophysiology of the hypoperfusion in Alzheimer's disease, BioLegend APP antibody (Covance, 11A50-B10) was used in ELISA on human samples at 1 ug/ml (fig 6). Brain Pathol (2016) ncbi |
mouse monoclonal (12F4) |
| In order to investigate the pathophysiology of the hypoperfusion in Alzheimer's disease, BioLegend APP antibody (Covance, 12F4) was used in ELISA on human samples at 1 ug/ml (fig 6). Brain Pathol (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, Ab1-16) was used in immunohistochemistry on mouse samples (fig 9a). PLoS ONE (2015) ncbi |
mouse monoclonal (6E10) |
| In order to determine the effects of traumatic brain injury in the presence and absence of beta-amyloid, BioLegend APP antibody (Signet Labs, 6E10) was used in western blot on mouse samples (fig 6a). J Neurotrauma (2016) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunoprecipitation on mouse samples . Acta Neuropathol Commun (2015) ncbi |
mouse monoclonal (4G8) |
| In order to characterize changes that occur during the accumulation of amyloid beta in artery walls, BioLegend APP antibody (Covance, SIG39220) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 3). Biochim Biophys Acta (2016) ncbi |
mouse monoclonal (6E10) |
| In order to characterize the neuropathologic evaluation of Alzheimer's disease by multisite assessment of NIA-AA guidelines, BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on human samples (tbl 1). Alzheimers Dement (2016) ncbi |
mouse monoclonal (4G8) |
| In order to characterize the neuropathologic evaluation of Alzheimer's disease by multisite assessment of NIA-AA guidelines, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples (tbl 1). Alzheimers Dement (2016) ncbi |
mouse monoclonal (M3.2) |
| In order to localize ADAM10 and BACE1 in synaptic vesicles, BioLegend APP antibody (BioLegend, SIG-39155) was used in western blot on rat samples at 1:1000. J Neurochem (2015) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the role of CCAAT/enhancer-binding protein delta in murine models of prion and Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39300) was used in western blot on mouse samples (fig 4). PLoS ONE (2015) ncbi |
mouse monoclonal (12F4) |
| BioLegend APP antibody (BioLegend Co, SIG-39142;) was used in western blot on mouse samples at 1:500 (fig 4). Ann Thorac Surg (2015) ncbi |
mouse monoclonal (12F4) |
| In order to investigate the link between prion disease and Alzheimer disease, BioLegend APP antibody (BioLegend Co, SIG-39142;) was used in western blot on mouse samples at 1:500 (fig 4). J Neuropathol Exp Neurol (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry on mouse samples at 1:100. Mol Neurodegener (2015) ncbi |
domestic rabbit polyclonal (Poly8134) | BioLegend APP antibody (BioLegend, 813401) was used . Proc Natl Acad Sci U S A (2015) ncbi | |
mouse monoclonal (M3.2) |
| BioLegend APP antibody (BioLegend, 805701) was used in immunoprecipitation on mouse samples at 1:300 and in western blot on mouse samples at 1:800. Proc Natl Acad Sci U S A (2015) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (BioLegend, 802802) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2015) ncbi |
mouse monoclonal (4G8) |
| In order to characterize the neuropathological features of dystonias, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry on human samples at 1:500. Tremor Other Hyperkinet Mov (N Y) (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet Laboratories, 6E-10) was used in western blot on fruit fly |
mouse monoclonal (4G8) | In order to classify subtypes of amyloid-beta oligomers, BioLegend APP antibody (Covance, SIG-39220) was used . Cell Rep (2015) ncbi | |
domestic rabbit monoclonal (1-11-3) | In order to classify subtypes of amyloid-beta oligomers, BioLegend APP antibody (Covance, SIG-39169) was used . Cell Rep (2015) ncbi | |
mouse monoclonal (6E10) | In order to classify subtypes of amyloid-beta oligomers, BioLegend APP antibody (Covance, SIG-39320) was used . Cell Rep (2015) ncbi | |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG-39200) was used in immunohistochemistry on mouse samples (fig 1f). PLoS ONE (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - free floating section on mouse samples at 1:200. Brain (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in other on human samples at 1:100 (fig 2a). J Neurochem (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - frozen section on human samples . Nucl Med Biol (2015) ncbi |
domestic rabbit monoclonal (1-11-3) |
| In order to develop and characterize a novel transgenic mouse model of Abeta toxicity, BioLegend APP antibody (Covance, SIG-39169) was used in western blot on mouse samples . PLoS ONE (2015) ncbi |
mouse monoclonal (LN27) |
| In order to develop and characterize a novel transgenic mouse model of Abeta toxicity, BioLegend APP antibody (Covance, SIG-39188) was used in western blot on mouse samples . PLoS ONE (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples . Biochemistry (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39340) was used in western blot on human samples . J Neurosci (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet, SIG-39300) was used in immunohistochemistry on mouse samples at 1:500. Brain Struct Funct (2016) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on rat samples . Biomed Res Int (2015) ncbi |
mouse monoclonal (4G8) |
| In order to explore a nonpharmacological approach, repeated scanning ultrasound treatments, for removing Abeta and restoring memory function in a mouse model of Alzheimer's disease, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - free floating section on mouse samples . Sci Transl Med (2015) ncbi |
mouse monoclonal (6E10) |
| In order to explore a nonpharmacological approach, repeated scanning ultrasound treatments, for removing Abeta and restoring memory function in a mouse model of Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:2000. Sci Transl Med (2015) ncbi |
mouse monoclonal (4G8) |
| In order to study neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease in mice, BioLegend APP antibody (Covance, 4G8) was used in western blot on human samples at 1:500. J Neuropathol Exp Neurol (2015) ncbi |
mouse monoclonal (6E10) |
| In order to elucidate the cell types and mechanisms underlying TREM2's contribution to neurodegeneration, BioLegend APP antibody (Covance, 6E10) was used in western blot on rat samples at 1:500. J Exp Med (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (biolegend, 803001) was used in western blot on mouse samples (fig 6e). Cell Death Differ (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:400. Neurobiol Aging (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG39220) was used in immunohistochemistry on human samples at 1:1000. F1000Res (2014) ncbi |
mouse monoclonal (6E10) |
| In order to assess the neuroprotective effect of quercetin administration in the triple transgenic Alzheimer's disease model mice, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:500. Neuropharmacology (2015) ncbi |
mouse monoclonal (C1/6.1) |
| In order to characterize cognitive and neuropathological Alzheimer's disease markers in a novel mouse model, BioLegend APP antibody (Covance, SIG-39152) was used in western blot on mouse samples at 1:1000 (fig 8). Age (Dordr) (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - paraffin section on mouse samples at 1:600. Alzheimer Dis Assoc Disord (2015) ncbi |
mouse monoclonal (4G8) |
| In order to investigate the relationship between beta-amyloid plaques and microglia, BioLegend APP antibody (BioLegend, SIG-39200) was used in immunohistochemistry on mouse samples (fig s2). Nat Commun (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on rat samples and in western blot on rat samples at 1:1000. J Exerc Nutrition Biochem (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - paraffin section on human samples at 1:300 and in ELISA on human samples at 1:1000. Neuropathol Appl Neurobiol (2015) ncbi |
mouse monoclonal (12F4) |
| BioLegend APP antibody (Covance, 12F4) was used in ELISA on human samples at 1:500. Neuropathol Appl Neurobiol (2015) ncbi |
mouse monoclonal (6E10) |
| In order to investigate hypercholesterolemia at various stages of Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39300) was used in immunohistochemistry on mouse samples at 1:1000. Mol Cell Neurosci (2014) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, Sig-39220) was used in immunohistochemistry on mouse samples at 1:150. Neurosci Lett (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Signet, #39240) was used in immunohistochemistry - frozen section on rat samples at 1:4000. Adv Alzheimer Dis (2014) ncbi |
mouse monoclonal (4G8) |
| In order to discuss decontaminating medical devices of pathological amyloid-beta-, tau- and alpha-synuclein aggregates, BioLegend APP antibody (Covance, SIG-39220) was used in western blot on human samples at 1:1000. Acta Neuropathol Commun (2014) ncbi |
mouse monoclonal (6E10) |
| In order to discuss decontaminating medical devices of pathological amyloid-beta-, tau- and alpha-synuclein aggregates, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples at 1:2000. Acta Neuropathol Commun (2014) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunocytochemistry on mouse samples at 1:1000. Neurobiol Aging (2015) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (Covance, C1/6.1) was used in western blot on mouse samples at 1:1000. Neurobiol Aging (2015) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunocytochemistry on mouse samples at 1:1000 and in western blot on mouse samples at 1:1000. Neurobiol Aging (2015) ncbi |
mouse monoclonal (6E10) |
| In order to study the impact of amyloid-beta oligomers in the brains of rats and adult cynomolgus macaques, BioLegend APP antibody (Covance, SIG-39300-200) was used in western blot on rhesus macaque samples at 1:1000. J Neurosci (2014) ncbi |
mouse monoclonal (4G8) |
| In order to study the impact of amyloid-beta oligomers in the brains of rats and adult cynomolgus macaques, BioLegend APP antibody (Covance, SIG-39220-200) was used in immunohistochemistry - free floating section on rat samples at 1:200. J Neurosci (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunocytochemistry on human samples , in ELISA on human samples and in western blot on human samples . J Biol Chem (2014) ncbi |
mouse monoclonal (4G8) |
| In order to investigate the role of membrane-anchored versus soluble CX3CL1 in regulating the microglia-mediated amelioration of Abeta pathology, BioLegend APP antibody (Signet Laboratories, SIG-39200-1000) was used in immunohistochemistry - free floating section on mouse samples at 1:250. J Neurosci (2014) ncbi |
mouse monoclonal (6E10) |
| In order to correlate TREM2 expression with neurodegenerative markers in Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - free floating section on human samples at 1:2500 and in western blot on human samples at 1:2500. Brain Pathol (2015) ncbi |
mouse monoclonal (C1/6.1) |
| In order to characterize brain aging in Alzheimer's disease and the biochemical properties of precuneus and posterior cingulate gyrus in the brain, BioLegend APP antibody (Covance, SIG-39152) was used in western blot on human samples (fig 1). PLoS ONE (2014) ncbi |
mouse monoclonal (1G6) |
| In order to characterize brain aging in Alzheimer's disease and the biochemical properties of precuneus and posterior cingulate gyrus in the brain, BioLegend APP antibody (Covance, SIG-39180) was used in western blot on human samples (fig 1). PLoS ONE (2014) ncbi |
mouse monoclonal (6E10) |
| In order to assess the effect of aging on brain lipoxin A4 levels using non-transgenic and 3xTg-AD mice, BioLegend APP antibody (Covance, 6E10) was used in immunocytochemistry on mouse samples . J Alzheimers Dis (2015) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on mouse samples at 1 ng/ ul and in ELISA on mouse samples . J Biol Chem (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in ELISA on mouse samples . J Biol Chem (2014) ncbi |
mouse monoclonal (4G8) |
| In order to investigate the relationship between ZnT3 and PSD95, cognition and pathology, BioLegend APP antibody (Covance, SIG-39220-200) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Neurobiol Aging (2014) ncbi |
mouse monoclonal (4G8) |
| In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, BioLegend APP antibody (Covance, 4G8) was used in immunoprecipitation on human samples , in ELISA on human samples and in western blot on human samples . Int J Alzheimers Dis (2014) ncbi |
mouse monoclonal (6E10) |
| In order to assess the presence of granulovacuolar degeneration and the activated unfolded protein response in two mouse models of Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in immunocytochemistry on human samples at 1:50. Neurobiol Dis (2014) ncbi |
mouse monoclonal (6E10) |
| In order to study the relationship of an Alzheimer's disease-linked SNP in the CLU gene and Tau, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples . PLoS ONE (2014) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the mechanism for the neuroprotective effect of Klotho, BioLegend APP antibody (Covance, SIG-39300) was used in western blot on mouse samples at 1:2000 and in western blot on rat samples at 1:2000. J Biol Chem (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:5000. PLoS ONE (2014) ncbi |
mouse monoclonal (6E10) |
| In order to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure, BioLegend APP antibody (Covance, SIG-39340) was used in western blot on mouse samples at 1:2500. J Neurosci (2014) ncbi |
mouse monoclonal (6E10) |
| In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:500. J Neurosci (2014) ncbi |
mouse monoclonal (4G8) |
| BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Alzheimers Dis (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on human samples at 1 ug/ml. J Alzheimers Dis (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:1000. Nanomedicine (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance Research Products, 6E10) was used in immunohistochemistry - free floating section on mouse samples and in western blot on mouse samples . Am J Pathol (2014) ncbi |
mouse monoclonal (6E10) |
| In order to evaluate a novel insulin/IGF signaling pathway inhibitor for its protective effect on age-onset, neurodegeneration-linked proteotoxicity, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples . Aging Cell (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance Inc., 6E10) was used in immunohistochemistry - frozen section on mouse samples at 1:1500. Acta Neuropathol Commun (2013) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - free floating section on mouse samples at 1:2000. J Alzheimers Dis (2014) ncbi |
mouse monoclonal (6E10) |
| In order to investigate the role of microglial derived tumor necrosis factor alpha in neuronal cell cycle progression, BioLegend APP antibody (Covance, SIG-39300) was used in immunoprecipitation on mouse samples . Neurobiol Dis (2014) ncbi |
mouse monoclonal (6E10) |
| In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on mouse samples at 1:1000. J Neurotrauma (2014) ncbi |
mouse monoclonal (6E10) |
| In order to study the role of NG2 oligodendroglial precursor cells in the autophagic removal of Abeta peptides, BioLegend APP antibody (Signet, sig-39320) was used in western blot on human samples at 1:1000. Mol Neurodegener (2013) ncbi |
mouse monoclonal (C1/6.1) |
| BioLegend APP antibody (Covance, SIG-39152) was used in western blot on mouse samples at 1:1000. Apoptosis (2013) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 and in western blot on mouse samples at 1:1000. Apoptosis (2013) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Signet, 6E10) was used in immunohistochemistry on mouse samples at 1:200. Transl Psychiatry (2013) ncbi |
mouse monoclonal (6E10) |
| In order to study the formation of amylin amyloid deposits in the cerebrovascular system and the implications for Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on human samples . Ann Neurol (2013) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - frozen section on human samples at 2 ug/ml. Neuropathol Appl Neurobiol (2014) ncbi |
mouse monoclonal (4G8) |
| In order to study changes in autophagy and the roles of Tau hyperphosphorylation and fractalkine in an animal model of Abeta42-induced Tau hyperphosphorylation, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:200. Exp Neurol (2014) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Convance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:200. J Alzheimers Dis (2013) ncbi |
mouse monoclonal (4G8) | In order to study the mechanism by which Gas1 blocks the intracellular trafficking of amyloid precursor protein, BioLegend APP antibody (Signet, 4G8) was used . J Alzheimers Dis (2012) ncbi | |
mouse monoclonal (6E10) |
| In order to investigate the role of growth arrest-specific 1 in Alzheimer's disease, BioLegend APP antibody (Signet, 6E10) was used in western blot on human samples . Hum Mol Genet (2011) ncbi |
mouse monoclonal (4G8) |
| In order to investigate the role of growth arrest-specific 1 in Alzheimer's disease, BioLegend APP antibody (Signet, 4G8) was used in immunoprecipitation on mouse samples . Hum Mol Genet (2011) ncbi |
mouse monoclonal (6E10) |
| BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples . Neurobiol Aging (2012) ncbi |
Invitrogen
domestic rabbit polyclonal (CT695) |
| Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot knockout validation on mouse samples at 1:250 (fig s1). Aging (Albany NY) (2021) ncbi |
domestic rabbit polyclonal (CT695) |
| Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples . Acta Neuropathol Commun (2021) ncbi |
domestic rabbit polyclonal (CT695) |
| Invitrogen APP antibody (hermoFisher, 51-2700) was used in immunohistochemistry on mouse samples at (fig 3b). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (22C11) |
| Invitrogen APP antibody (Thermo Fisher, 22C11) was used in immunohistochemistry - paraffin section on rat samples at 1:250 (fig 6a). Histochem Cell Biol (2019) ncbi |
mouse monoclonal (NAB228) |
| Invitrogen APP antibody (ThermoFisher Scientific, NAB228) was used in immunocytochemistry on human samples (fig 2a) and in western blot on human samples (fig 1b). J Biol Chem (2019) ncbi |
domestic rabbit polyclonal |
| Invitrogen APP antibody (Zymed/Thermo Fisher Scientific, 71-5800) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig s1a). Am J Pathol (2018) ncbi |
domestic rabbit recombinant (H31L21) |
| Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - frozen section on African green monkey samples at 1:2500 (fig 1d). Neurobiol Aging (2017) ncbi |
domestic rabbit recombinant (H31L21) |
| Invitrogen APP antibody (Invitrogen, 700254) was used in western blot on human samples (fig 6b). PLoS Genet (2017) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to characterize physiological conformations of Abeta and amyloid precursor protein, Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (fig st1). Nat Commun (2017) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to characterize physiological conformations of Abeta and amyloid precursor protein, Invitrogen APP antibody (ThermoFisher, OMA1-03132) was used in western blot on mouse samples at 1:1000 (fig st1). Nat Commun (2017) ncbi |
domestic rabbit polyclonal (CT695) |
| In order to characterize gyrencephalic swine brains exposed to true open field blasts, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on pigs |
domestic rabbit polyclonal |
| In order to assess the effects of choline using a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 44-344) was used in immunohistochemistry on mouse samples at 1:2500 (fig 4a). PLoS ONE (2017) ncbi |
domestic rabbit polyclonal |
| In order to evaluate cellular markers associated with neurodegenerative diseases in common marmoset (Callithrix jacchus) brains, Invitrogen APP antibody (Invitrogen, 44136) was used in immunohistochemistry - frozen section on African green monkey samples at 1:200 (fig 1h). Front Aging Neurosci (2016) ncbi |
domestic rabbit polyclonal |
| In order to evaluate cellular markers associated with neurodegenerative diseases in common marmoset (Callithrix jacchus) brains, Invitrogen APP antibody (Invitrogen, 44344) was used in immunohistochemistry - frozen section on African green monkey samples at 1:200 (fig 1f). Front Aging Neurosci (2016) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to describe an alternative aminomethyl linker for beta-secretase inhibitors that with potency similar to the current anilide moiety and improves brain penetration, Invitrogen APP antibody (Affinity BioReagents, OMA1-03132) was used in ELISA on human samples . J Med Chem (2017) ncbi |
domestic rabbit polyclonal (CT695) |
| In order to describe functional and structural pathology-to-network signatures in the brain after cuprizone treatment, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples (fig 2e). Neuroimage (2017) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to investigate if amyloid beta 40 or 42 is related to sustaining a traumatic brain injury or to chronic neurological symptoms in a young cohort of military personnel, Invitrogen APP antibody (Invitrogen, H31L21) was used in ELISA on human samples (fig 1a). Brain Inj (2016) ncbi |
mouse monoclonal (BAM01 (6F/3D)) |
| In order to characterize preclinical subjects with corticobasal degeneration, Invitrogen APP antibody (Biosource international, 6F/3D) was used in immunohistochemistry on human samples at 1:100 (tbl 1). Brain (2016) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to identify autophagy-inducing phytochemicals, Invitrogen APP antibody (Invitrogen, 700254) was used in dot blot on mouse samples at 1:1000 (fig 6a) and in immunohistochemistry on mouse samples at 1:500 (fig 6b). Autophagy (2017) ncbi |
domestic rabbit polyclonal (CT695) |
| In order to suggest that loss of the Wnt signaling pathway may contribute to Alzheimer's disease pathogenesis, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples (fig 3b). J Neurochem (2016) ncbi |
domestic rabbit polyclonal |
| In order to discuss the role of corticotropin-releasing factor in the sex bias of some neuropsychiatric and neurodegenerative disorders, Invitrogen APP antibody (ThermoFisher Scientific, 44136) was used in immunohistochemistry on human samples at 1:1000 (fig 4d). Mol Psychiatry (2017) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to demonstrate that cathepsin D is an off-target of BACE1 inhibitors in human cells, Invitrogen APP antibody (Affinity BioReagents, OMA1-03132) was used in ELISA on human samples . Nat Commun (2016) ncbi |
domestic rabbit polyclonal (CT695) |
| In order to show that Egr-1 plays role in BACE-1 activation, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples (fig 3a). J Biol Chem (2016) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to report that reduced exosome secretion due to nSMase2 loss improves pathology and cognition in a mouse model of Alzheimer's disease, Invitrogen APP antibody (ThermoFisher, H31L21) was used in immunohistochemistry on mouse samples (fig 2a), in ELISA on mouse samples (fig 5a) and in western blot on mouse samples (fig 1f). J Neurosci (2016) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to propose that the fornix plays a role in Alzheimer's disease, Invitrogen APP antibody (Life Technology, H31L21) was used in immunohistochemistry on mouse samples (fig 7e). Neuroimage (2016) ncbi |
domestic rabbit polyclonal |
| In order to study a novel platform based on the planar frequency mixing magnetic technique that is a magnetic immunoassay, Invitrogen APP antibody (Invitrogen, 44-344) was used in other on human samples at 1:300 (fig 2). Biosens Bioelectron (2016) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to test if the beta-amyloid peptide disrupts microtubules, Invitrogen APP antibody (ThermoFisher, 700254) was used in immunocytochemistry on mouse samples at 1:600 (fig 1b). Acta Neuropathol (2016) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to characterize the frontal cortex of wild mountain gorillas (Gorilla beringei beringei) for early Alzheimer's disease-type pathology, Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - free floating section on human samples at 1:100 (tbl 2). Neurobiol Aging (2016) ncbi |
domestic rabbit polyclonal |
| In order to characterize chronic white matter inflammation and dendritic spine loss in a mouse model of highly repetitive head trauma, Invitrogen APP antibody (Invitrogen, 36-6900) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 4). Am J Pathol (2016) ncbi |
domestic rabbit polyclonal |
| In order to study colocalization of A-beta pathology in Alzheimer's disease mouse models with catalytically active tissue transglutaminase, Invitrogen APP antibody (Invitrogen, 715800) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 1). Sci Rep (2016) ncbi |
domestic rabbit polyclonal (CT695) |
| In order to characterize organelles that bind microtubules in an ATP dependent manner by studying the amyloid precursor protein of Alzheimer's disease clusters at the organelle/microtubule interface, Invitrogen APP antibody (Invitrogen, 51-C2700) was used in immunocytochemistry on longfin inshore squid samples (fig 1). PLoS ONE (2016) ncbi |
mouse monoclonal (LN27) |
| In order to study cargo deficits in multiple sclerosis lesional and normal-appearing white matter for the axonal motor protein KIF5A, Invitrogen APP antibody (Zymed, 13-0200) was used in western blot on human samples at 1:500 (fig 3). Neuropathol Appl Neurobiol (2017) ncbi |
mouse monoclonal (LN27) |
| In order to analyze chemogenetic modulation of neural activity by attenuation of beta-amyloid deposition and neurotoxicity, Invitrogen APP antibody (Thermo Fisher, LN27) was used in immunohistochemistry on human samples (fig 7). J Neurosci (2016) ncbi |
domestic rabbit polyclonal (CT695) | In order to assess the deletion of Ccr2 and cavity size and tau pathology after mild traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used . J Neuroinflammation (2015) ncbi | |
domestic rabbit polyclonal |
| In order to determine how an increase in synapse AMPA subuit and amelioration of spatial memory deficits occurs by TrkB activation by 7,8-dihydroxyflavone in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Thermo Scientific, PA3-16760) was used in western blot on mouse samples at 1:500 (tbl 1). J Neurochem (2016) ncbi |
domestic rabbit polyclonal | In order to investigate the contribution of TRPM2 to beta-amyloid neuronal toxicity, Invitrogen APP antibody (Invitrogen, 44344) was used . J Neurosci (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to assess Losartan treatment on experimental glaucoma, Invitrogen APP antibody (Novex by Life Technologies, 512700) was used . PLoS ONE (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to determine the relationship between injured axons after mild traumatic brain injury in pigs and microglia processes, Invitrogen APP antibody (Life Technologies, 51-2700) was used . J Neuroinflammation (2015) ncbi | |
mouse monoclonal (LN27) |
| In order to investigate the role of cholesterol in the pathogenesis of Alzheimer's disease, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples at 1:400. J Neurodegener Dis (2013) ncbi |
domestic rabbit polyclonal (CT695) | In order to elucidate the mechanisms by which increased LMNB1 levels cause autosomal dominant leukodystrophy, Invitrogen APP antibody (Invitrogen, 512700) was used . J Neurosci (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to show that IDN5706 promotes iAPP degradation by activating Atg5-dependent autophagy, Invitrogen APP antibody (Invitrogen, 51-2700) was used . PLoS ONE (2015) ncbi | |
mouse monoclonal (LN27) |
| In order to analyze a mouse model where human neural stem cells alleviate Alzheimer-like pathology, Invitrogen APP antibody (Zymed, 130200) was used in western blot on mouse samples at 1:1000 (fig 4). Mol Neurodegener (2015) ncbi |
domestic rabbit polyclonal | In order to demonstrate that liraglutide has prophylactic properties in Alzheimer's disease models, Invitrogen APP antibody (Invitrogen, 71-5800) was used . Behav Brain Res (2015) ncbi | |
domestic rabbit polyclonal | In order to study the role of apolipoprotein E in cerebral amyloid angiopathy, Invitrogen APP antibody (Invitrogen, 715800) was used . J Neurochem (2015) ncbi | |
domestic rabbit polyclonal | In order to classify subtypes of amyloid-beta oligomers, Invitrogen APP antibody (Invitrogen, 36-6900) was used . Cell Rep (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to describe the development of a closed-body model of spinal cord injury in mice, Invitrogen APP antibody (Invitrogen, 51-2700) was used . Exp Neurol (2015) ncbi | |
domestic rabbit polyclonal | In order to investigate butyrylcholinesterase activity in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used . Neuroscience (2015) ncbi | |
domestic rabbit recombinant (H31L21) |
| Invitrogen APP antibody (Invitrogen, H31L21) was used in immunohistochemistry - frozen section on mouse samples . J Neurosci (2015) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to generate BACE1 inhibitors for the treatment of Alzheimer's disease, Invitrogen APP antibody (Affinity BioReagents, OMA1-03132) was used in ELISA on human samples (fig 1). J Med Chem (2015) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the spread of neuronal pathology, Invitrogen APP antibody (Life Technologies, 13-0200) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Neuropathol Appl Neurobiol (2015) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to generate and characterize new BACE1 inhibitors for the treatment of Alzheimer's disease, Invitrogen APP antibody (Affinity BioReagents, OMA1-03132) was used in ELISA on human samples (tbl 1). J Med Chem (2015) ncbi |
domestic rabbit polyclonal (CT695) | In order to discuss the limitations assessing axonal injury by microscopy, Invitrogen APP antibody (Invitrogen, 51-2700) was used . J Neurosci Methods (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to investigate the contribution of TREM2 to microglia function in vivo, Invitrogen APP antibody (Invitrogen, 51-2700) was used . Acta Neuropathol (2015) ncbi | |
domestic rabbit recombinant (H31L21) |
| In order to quantify amyloid beta 42 and paired helical filament-tau in the frontal, temporal, and parietal cortices, Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - paraffin section on human samples (fig 4). J Neuropathol Exp Neurol (2015) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to test if reduction in BACE1 prevents or treats Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 700254) was used in ELISA on mouse samples (fig 3) and in western blot on mouse samples at 1:2500 (fig 2). Mol Neurodegener (2015) ncbi |
domestic rabbit polyclonal (CT695) | In order to characterize axonal injury over time, Invitrogen APP antibody (Invitrogen, 51-2700) was used . Acta Neuropathol (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to examine the role of the monoaminergic system in mild blast-induced traumatic brain injury, Invitrogen APP antibody (Life Technologies, 51-2700) was used . J Neurotrauma (2015) ncbi | |
domestic rabbit polyclonal (CT695) | In order to report that Kal9 and Kal12 mediate dendritic maturation in early development, Invitrogen APP antibody (Life Technologies, 51-2700) was used . Cereb Cortex (2015) ncbi | |
domestic rabbit recombinant (H31L21) |
| In order to investigate the contribution of GABA inhibition in the dentate gyrus in Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 700254) was used in immunocytochemistry on human samples at 1:2000. Nat Commun (2014) ncbi |
mouse monoclonal (BAM01 (6F/3D)) |
| In order to investigate the protein expression of G-CSF and its receptor in the adult human brain, Invitrogen APP antibody (Pierce Biotechnology, Clone 6F/3D) was used in immunohistochemistry on human samples at 1:100. J Anat (2014) ncbi |
mouse monoclonal (LN27) |
| In order to explain how CCR5 antagonists may attenuate central nervous system disease by modulating inflammatory signaling and by limiting HIV replication, Invitrogen APP antibody (Zymed, Clone LN27) was used in immunohistochemistry on rhesus macaque samples (fig 4). AIDS (2013) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurotrauma (2014) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to study the role of NG2 oligodendroglial precursor cells in the autophagic removal of Abeta peptides, Invitrogen APP antibody (Invitrogen, 700254) was used in immunocytochemistry on human samples and in western blot on human samples . Mol Neurodegener (2013) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to study levels of BACE1 and Abeta42 in aged patients with cerebral atherosclerosis in the absence of dementia, Invitrogen APP antibody (Invitrogen, 700254) was used in western blot on human samples at 1:2500. Curr Alzheimer Res (2013) ncbi |
mouse monoclonal (LN27) |
| In order to identify agents that can reduce Abeta levels in the brain, Invitrogen APP antibody (Invitrogen, LN27) was used in western blot on human samples (fig 1). J Biol Chem (2013) ncbi |
mouse monoclonal (LN27) |
| In order to describe the intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system, Invitrogen APP antibody (Zymed, LN27) was used in immunocytochemistry on human samples . Transl Neurodegener (2012) ncbi |
mouse monoclonal (LN27) |
| In order to elucidate the molecular linkage between epileptic seizures and Abeta generation in Alzheimer's disease, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples (fig 6b). Mol Neurodegener (2012) ncbi |
domestic rabbit polyclonal | In order to examine the effect on the anti-inflammatory, MW01-2-151SRM, in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 44338100) was used . J Neurosci (2012) ncbi | |
mouse monoclonal (LN27) |
| In order to study the role of receptor tyrosine kinase Tyro3 in APP processing and beta amyloid deposition, Invitrogen APP antibody (ZYMED, 13-0200) was used in western blot on human samples at 1:1000 (fig 3, 4). PLoS ONE (2012) ncbi |
mouse monoclonal (LN27) |
| In order to elucidate the role of Kinesin-1 in Alzheimer disease pathogenesis, Invitrogen APP antibody (Invitrogen, LN27) was used in western blot on human samples at 1:250 (fig 3). PLoS ONE (2012) ncbi |
domestic rabbit recombinant (H31L21) |
| In order to study the effects of hypoxia following cardiac arrest on Abeta42 serum levels in humans, Invitrogen APP antibody (Invitrogen, H31L21) was used in ELISA on human samples at 0.1 ug/ml. PLoS ONE (2011) ncbi |
mouse monoclonal (LN27) |
| In order to investigate phagocytosis of neuronal antigens in a multiple sclerosis model, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry on human samples (tbl 2). Glia (2012) ncbi |
mouse monoclonal (LN27) |
| In order to study the contribution of macroautophagy to lysosomal Abeta accumulation, Invitrogen APP antibody (Zymed Laboratories, 13-0200) was used in immunocytochemistry on human samples at 1:100 (fig 1). Autophagy (2011) ncbi |
mouse monoclonal (LN27) |
| In order to study the mechanism by which Gas1 blocks the intracellular trafficking of amyloid precursor protein, Invitrogen APP antibody (Zymed Laboratories, LN27) was used in western blot on human samples (fig 1). J Alzheimers Dis (2012) ncbi |
mouse monoclonal (LN27) |
| In order to identify and characterize LDL receptor class A domain containing 3, Invitrogen APP antibody (Zymed, clone LN27) was used in immunocytochemistry on mouse samples (fig 7). J Neurosci (2011) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the role of growth arrest-specific 1 in Alzheimer's disease, Invitrogen APP antibody (Zymed Laboratories, LN27) was used in immunocytochemistry on human samples and in western blot on human samples . Hum Mol Genet (2011) ncbi |
mouse monoclonal (LN27) |
| In order to compare the serum immunoglobulin G reactivity profiles obtained using the full spectrum of human myelin-associated proteins of multiple sclerosis patients and healthy control subjects, Invitrogen APP antibody (Zymed, clone LN27) was used in western blot on human samples . J Neuropathol Exp Neurol (2010) ncbi |
mouse monoclonal (LN27) |
| In order to investigate resveratrol's regulation of AMP-activated protein kinase, Invitrogen APP antibody (Zymed Laboratories, LN27) was used in immunocytochemistry on mouse samples . J Biol Chem (2010) ncbi |
mouse monoclonal (LN27) |
| In order to search for N-terminal fragments of amyloid precursor protein in cerebrospinal fluid, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples . Exp Neurol (2010) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to search for N-terminal fragments of amyloid precursor protein in cerebrospinal fluid, Invitrogen APP antibody (BioSource, P2-1) was used in immunoprecipitation on human samples . Exp Neurol (2010) ncbi |
mouse monoclonal (LN27) |
| In order to assess the relationship between expression of the MHC class I allele Mane-A*10 and development of lentiviral-induced central nervous system disease, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on rhesus macaque samples (fig 1). PLoS ONE (2008) ncbi |
mouse monoclonal (LN27) |
| In order to study the case of a 61-year-old man with autosomal dominant sensory ataxia who died of congestive heart failure, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry on human samples (fig 1). Acta Neuropathol (2008) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A in Down syndrome brains, Invitrogen APP antibody (Zymed Laboratories, 13-0200) was used in immunocytochemistry on human samples (fig 2). J Neurochem (2008) ncbi |
mouse monoclonal (LN27) |
| In order to examine the role of calpain activation in the corpus callosum in traumatic brain injury, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on rat samples at 1:200. J Neurotrauma (2007) ncbi |
mouse monoclonal (LN27) |
| In order to test if sporadic cases of Alzheimer's disease are associated with changes in transcription of amyloid precursor protein or its metabolic partners, Invitrogen APP antibody (Zymed, LN27) was used in ELISA on human samples at 0.5 ug/ml. Brain Res (2007) ncbi |
mouse monoclonal (LN27) |
| In order to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle, Invitrogen APP antibody (Zymed, 13-0200) was used in immunocytochemistry on human samples at 1:1000. J Biol Chem (2007) ncbi |
mouse monoclonal (LN27) |
| In order to examine brain material from four fatal human cases of Japanese encephalitis virus infection, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples at 1:1500 and in immunohistochemistry - paraffin section on mouse samples at 1:1500 (fig 8). Trans R Soc Trop Med Hyg (2006) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the effect of L-glutamate treatment on the secreted form of amyloid precursor protein, Invitrogen APP antibody (Zymed, LN27) was used in western blot on rat samples (fig 2). Acta Biol Hung (2005) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the role 14-3-3 proteins in the pathogenesis of central nervous system, Invitrogen APP antibody (Zymed, Clone LN27) was used in immunohistochemistry on rhesus macaque samples at 1:10000. J Neuropathol Exp Neurol (2005) ncbi |
mouse monoclonal (LN27) |
| In order to present the case of a Japanese patient who had a prion protein gene mutation responsible for fatal familial insomnia, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples (fig 5). Neuropathol Appl Neurobiol (2005) ncbi |
mouse monoclonal (AMY-33) |
| In order to use intracerebroventricular injection of anti-Abeta antibody to treat murine models of Alzheimer's disease, Invitrogen APP antibody (ZyMed, AMY-33) was used in ELISA on human samples . Expert Rev Vaccines (2004) ncbi |
mouse monoclonal (LN27) |
| In order to develop and characterize a new mouse model of Alzheimer's disease, Invitrogen APP antibody (Zymed, 13-0200) was used in immunohistochemistry - paraffin section on mouse samples (fig 2) and in western blot on mouse samples (fig 2). J Neurosci Res (2004) ncbi |
mouse monoclonal (LN27) |
| In order to determine the soluble molecules in cerebrospinal fluid that indicate axonal degeneration and amyloidogenesis, Invitrogen APP antibody (Zymed, LN27) was used in ELISA on human samples . Arthritis Res Ther (2004) ncbi |
mouse monoclonal (LN27) |
| In order to characterize mice that overexpress the Swedish double familial Alzheimer's disease mutation, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples (fig 1). Neuroscience (2003) ncbi |
mouse monoclonal (LN27) |
| In order to describe a biomechanical study of axonal injury due to a blunt impact to the head, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on domestic sheep samples (fig 3). J Neurotrauma (2003) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the role of Alcadein in Alzheimer's disease, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples (fig 3). J Biol Chem (2003) ncbi |
mouse monoclonal (LN27) |
| In order to investigate HIV/SIV CNS infection and damage, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry on human samples (tbl 2). J Neurovirol (2003) ncbi |
mouse monoclonal (mAbP2-1) |
| In order to investigate the role of the -YENP- motif of the amyloid precursor protein, Invitrogen APP antibody (Biosource, mAbP2-1) was used in ELISA on human samples at 0.25 ug/ml. Neuroscience (2003) ncbi |
mouse monoclonal (AMY-33) |
| In order to test if caspase-3-mediated cleavage of beta-amyloid precursor protein occurs in traumatic axonal injury, Invitrogen APP antibody (Zymed, AMY-33) was used in immunohistochemistry on rat samples (fig 4). J Neurotrauma (2002) ncbi |
mouse monoclonal (LN27) |
| In order to investigate the mechanisms of axonal damage associated with HIV central nervous system infection, Invitrogen APP antibody (Zymed Laboratories, Clone LN27) was used in immunohistochemistry on pigtail macaque samples (fig 1). J Neuropathol Exp Neurol (2002) ncbi |
mouse monoclonal (LN27) |
| In order to determine the role of endocytic compartments in beta-secretase processing of amyloid precursor protein, Invitrogen APP antibody (Zymed, clone LN27) was used in western blot on human samples (fig 6). Traffic (2001) ncbi |
mouse monoclonal (LN27) |
| In order to examine MG132 inhibition of beta-secretase cleavage, Invitrogen APP antibody (Zymed, LN27) was used in ELISA on human samples . J Biol Chem (2001) ncbi |
mouse monoclonal (LN27) |
| In order to elucidate the regulatory role of human bleomycin hydrolase in the amyloid precursor protein processing pathways, Invitrogen APP antibody (Zymed Laboratories, clone LN27) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig 8). FASEB J (2000) ncbi |
mouse monoclonal (LN27) |
| In order to characterize human X11-like, Invitrogen APP antibody (Zymed, LN27) was used in immunocytochemistry on human samples (fig 8). J Biol Chem (1999) ncbi |
mouse monoclonal (LN27) |
| In order to study aluminum maltolate-induced neurofibrillary degeneration in rabbits, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on domestic rabbit samples at 1:200 (fig 1) and in western blot on domestic rabbit samples at 1:1000 (fig 2). Brain Res (1997) ncbi |
mouse monoclonal (AMY-33) |
| In order to examine beta-amyloid formation and its inhibition, Invitrogen APP antibody (Zymed, AMY-33) was used in immunoprecipitation on human samples (fig 3). Proc Natl Acad Sci U S A (1996) ncbi |
mouse monoclonal (LN27) |
| In order to investigate markers of axonal injury, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples at 1:200. Acta Neuropathol (1994) ncbi |
mouse monoclonal (LN27) |
| In order to study 3B11 immunoreactivity in the human brain, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples at 1:200. Biochem J (1995) ncbi |
Abcam
domestic rabbit monoclonal (mOC64) |
| Abcam APP antibody (Abcam, ab201060) was used in western blot on human samples (fig 4a), in immunohistochemistry on rhesus macaque samples (fig 2a, 2b) and in western blot on rhesus macaque samples (fig 1a, 1b). Aging Dis (2021) ncbi |
domestic rabbit polyclonal |
| Abcam APP antibody (Abcam, ab15272) was used in western blot on human samples (fig 4b). Aging Dis (2021) ncbi |
domestic rabbit monoclonal (mOC64) |
| Abcam APP antibody (Abcam, ab201060) was used in western blot on mouse samples at 1:1000 (fig 5a). PLoS ONE (2021) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry on mouse samples at 1:500. Acta Neuropathol Commun (2020) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on mouse samples at 1:1000 (fig 5a). Acta Neuropathol Commun (2020) ncbi |
domestic rabbit polyclonal |
| Abcam APP antibody (Abcam, ab2072) was used in western blot on mouse samples at 1:1000 (fig 5a). Acta Neuropathol Commun (2020) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry - frozen section on mouse samples at 1:150 (fig 3b) and in western blot on mouse samples at 1:2000 (fig 3f). Front Aging Neurosci (2020) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 5a, 5d). Sci Adv (2020) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry - paraffin section on mouse samples at 1:15,000 (fig 4). J Neurotrauma (2020) ncbi |
mouse monoclonal (MOAB-2) |
| Abcam APP antibody (Abcam, ab126649) was used in immunohistochemistry - frozen section on mouse samples at 1:400 (fig 1b). Nat Commun (2019) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4c), in immunocytochemistry on mouse samples at 1:200 (fig 1b), in western blot on mouse samples (fig 1c), in immunocytochemistry on human samples at 1:200 (fig 2b) and in western blot on human samples (fig 2c). Nat Commun (2019) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on human samples (fig 1b). J Biol Chem (2019) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Y188) was used in immunohistochemistry on mouse samples (fig 5). Front Cell Neurosci (2018) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on mouse samples (fig 1a). Sci Transl Med (2018) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Y188) was used in western blot on mouse samples at 1:2000 (fig 4b). Mol Neurodegener (2018) ncbi |
domestic rabbit monoclonal (mOC64) |
| Abcam APP antibody (Abcam, ab201060) was used in western blot on mouse samples (fig 3f). Neurotherapeutics (2018) ncbi |
domestic rabbit monoclonal (Y188) |
| In order to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease, Abcam APP antibody (Abcam, ab32136) was used in immunocytochemistry on pigs |
mouse monoclonal (DE2B4) |
| In order to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease, Abcam APP antibody (Abcam, ab11132) was used in immunocytochemistry on pigs |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on mouse samples (fig 5b). Sci Rep (2017) ncbi |
domestic rabbit polyclonal |
| Abcam APP antibody (Abcam, ab15272) was used in western blot on human samples (fig 4a). elife (2017) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Epitomics, ab32136) was used in immunohistochemistry knockout validation on mouse samples (fig 1e), in western blot knockout validation on mouse samples (fig 2) and in immunohistochemistry - free floating section on mouse samples (fig 1d). Front Mol Neurosci (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| In order to investigate how familial Alzheimer's disease mutations affect endocytosis, Abcam APP antibody (Abcam, ab32136) was used in immunocytochemistry on human samples at 1:200 (fig 1a). Cell Rep (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 4) and in western blot on rat samples at 1:1000 (fig 3). Neural Regen Res (2016) ncbi |
mouse monoclonal (DE2B4) |
| Abcam APP antibody (Abcam, ab11132) was used in western blot on human samples (fig 1). Aging Cell (2016) ncbi |
domestic rabbit monoclonal (Y188) | In order to study behavioral deficits without pathological interaction by humanized tau mice with regionalized amyloid, Abcam APP antibody (Abcam, ab32136) was used . PLoS ONE (2016) ncbi | |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in western blot on human samples at 1:4000 (fig 1). EMBO Mol Med (2016) ncbi |
domestic rabbit polyclonal |
| In order to research blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer's brains by pharmacological profiling of the novel modulator of the alpha7 nicotinic receptor, Abcam APP antibody (Abcam, ab2072) was used in western blot on rat samples at 1:1000 (fig 2). Neuropharmacology (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunocytochemistry on mouse samples (fig 3a). Nat Neurosci (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| In order to localize ADAM10 and BACE1 in synaptic vesicles, Abcam APP antibody (Abcam, ab32136) was used in western blot on rat samples at 1:5000. J Neurochem (2015) ncbi |
mouse monoclonal (BDI350) |
| Abcam APP antibody (Abcam, ab20068) was used in western blot on mouse samples . J Inorg Biochem (2015) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry on mouse samples at 1:1000. J Neuroimmunol (2015) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Ab32136) was used in immunohistochemistry on mouse samples (fig 3c) and in western blot on mouse samples at 1:1000 (fig 3a). PLoS ONE (2015) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, ab32136) was used in ELISA on human samples (tbl 4), in western blot on human samples (tbl 4) and in western blot on mouse samples (tbl 3). Biogerontology (2015) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Y188) was used in immunohistochemistry - paraffin section on mouse samples , in immunoprecipitation on mouse samples and in western blot on mouse samples . Front Cell Neurosci (2015) ncbi |
domestic rabbit monoclonal (Y188) |
| In order to assess the effect of CD11b-positive (+) monocytes on Alzheimer's disease using a mouse model, Abcam APP antibody (Abcam, ab32136) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi |
domestic rabbit polyclonal |
| Abcam APP antibody (Abcam, ab15272) was used in western blot on rat samples at 1:1000. Mol Neurobiol (2016) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Y188) was used in immunocytochemistry on human samples . J Biol Chem (2014) ncbi |
domestic rabbit monoclonal (Y188) |
| Abcam APP antibody (Abcam, Y188) was used in western blot on mouse samples . J Neurosci (2014) ncbi |
mouse monoclonal (DE2B4) |
| Abcam APP antibody (Abcam, AB11132) was used in immunohistochemistry - free floating section on mouse samples . Brain Behav (2013) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (B-4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, SC-28365) was used in western blot on human samples at 1:1000. Nat Commun (2021) ncbi |
mouse monoclonal (NAB228) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, sc-32277) was used in immunohistochemistry - free floating section on mouse samples at 1:2000 (fig 9a). elife (2020) ncbi |
mouse monoclonal (B-4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz Biotechnology, sc-28365) was used in western blot on rat samples at 1:200 (fig 5a). Neuropharmacology (2019) ncbi |
mouse monoclonal (DE2B4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, sc-58508) was used in immunohistochemistry on mouse samples at 1:250 (fig 6a). Cell Death Differ (2017) ncbi |
mouse monoclonal (B-4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, SC-28365) was used in western blot on rat samples (fig 5). Neural Plast (2016) ncbi |
mouse monoclonal (DE2B4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, sc-58508) was used in immunohistochemistry on fruit fly |
mouse monoclonal (B-4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, sc-28365) was used in proximity ligation assay on mouse samples at 2000 ng/ml (fig 5) and in western blot on mouse samples at 1000 ng/ml (fig 8). Nat Commun (2015) ncbi |
mouse monoclonal (20.1) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz Biotechnology, sc-53822) was used in western blot on human samples . Cell Mol Life Sci (2016) ncbi |
mouse monoclonal (DE2B4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz, DE2B4) was used in western blot on human samples at 1:1000 (fig 7). J Pineal Res (2015) ncbi |
mouse monoclonal (DE2B4) |
| Santa Cruz Biotechnology APP antibody (Santa Cruz Biotechnology, DE2B4) was used in western blot on human samples at 1:500. J Pineal Res (2015) ncbi |
mouse monoclonal (NAB228) |
| In order to determine the expression of abnormal serine phosphorylation of insulin receptor substrate 1 in healthy and diseased human brains, Santa Cruz Biotechnology APP antibody (Santa Cruz, 3227) was used in immunohistochemistry - paraffin section on human samples at 1:500. Acta Neuropathol (2014) ncbi |
Agrisera
mouse monoclonal (IgM) |
| Agrisera APP antibody (Agrisera, OMAB) was used in dot blot on mouse samples at 1:800 (fig 5a). Int J Mol Sci (2020) ncbi |
mouse monoclonal (IgM) |
| Agrisera APP antibody (Agrisera, AS10 932) was used in western blot on rhesus macaque samples at 1:1000 (fig 1d). Aging Cell (2019) ncbi |
Synaptic Systems
mouse monoclonal (88B12) |
| Synaptic Systems APP antibody (Synaptic Systems, 218711) was used in western blot on mouse samples at 1:500 (fig 4a). Neurobiol Learn Mem (2019) ncbi |
domestic rabbit polyclonal |
| Synaptic Systems APP antibody (Synaptic Systems, 218703) was used in immunohistochemistry - paraffin section on human samples (fig 2). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (326F12) |
| Synaptic Systems APP antibody (Synaptic Systems, 218421) was used in immunohistochemistry - paraffin section on human samples (fig 1). Acta Neuropathol Commun (2016) ncbi |
MABTECH
mouse monoclonal (bmAbetaN) |
| MABTECH APP antibody (Mabtech, 3740-5-250) was used in immunohistochemistry - frozen section on fruit fly |
mouse monoclonal (bmAbetaN) |
| MABTECH APP antibody (Mabtech, 3740-6-1000) was used in ELISA on human samples (fig 2,4). Biosens Bioelectron (2015) ncbi |
Bio-Rad
mouse monoclonal (DE2B4) |
| Bio-Rad APP antibody (AbD Serotec, MCA2172) was used in western blot on human samples (fig 3b). Oncotarget (2015) ncbi |
Cell Signaling Technology
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling Technologies, 8243S) was used in immunohistochemistry on mouse samples at 1:500 (fig 4c). J Biol Chem (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 2452) was used in western blot on mouse samples (fig s3e). Sci Adv (2021) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 8243S) was used in immunohistochemistry - free floating section on mouse samples at 1:400 (fig 4e). Sci Adv (2021) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling, 8243) was used in western blot on mouse samples (fig 3e). Front Cell Neurosci (2020) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling, D54D2) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig s7b). Nature (2020) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 2452S) was used in immunohistochemistry on human samples at 1:300 (fig 1a) and in western blot on human samples (fig 1dd-1). Int J Mol Med (2019) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (CELL SIGNALING, 8243s) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Front Neurosci (2019) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 8243) was used in immunohistochemistry on human samples at 1:500. Nature (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling, 2454) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig 1c). Nat Neurosci (2019) ncbi |
monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (CST, 51374) was used in immunohistochemistry on mouse samples (fig 7g). Cell (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 2452) was used in western blot on mouse samples (fig 3e). Sci Adv (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling Technology, 2452S) was used in western blot on mouse samples (fig 6b). Neurotherapeutics (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling, 2454) was used in immunohistochemistry - frozen section on rat samples at 1:500 (fig 3e) and in western blot on rat samples (fig 3a). J Biol Chem (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology APP antibody (Cell Signaling, 2454) was used in immunohistochemistry - free floating section on mouse samples at 1:250 (fig 2a). J Neurosci (2017) ncbi |
domestic rabbit polyclonal |
| In order to see that the granulin Alzheimer's disease risk variant has no significant effects on florbetapir positron emission tomographic amyloid imaging and cerebrospinal fluid Abeta levels, Cell Signaling Technology APP antibody (Cell Signaling, 2454) was used in immunohistochemistry on mouse samples at 1:500 (fig 2a). Acta Neuropathol (2017) ncbi |
domestic rabbit monoclonal (D90B8) |
| Cell Signaling Technology APP antibody (cell signalling, 6986) was used in western blot on mouse samples (fig 5). Int J Mol Med (2017) ncbi |
domestic rabbit polyclonal |
| In order to identify and characterize a DYRK1A inhibitor, Cell Signaling Technology APP antibody (Cell Signaling, 2452) was used in western blot on human samples at 1:1000 (fig 4). Dis Model Mech (2016) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling, 8243) was used in immunocytochemistry on mouse samples at 1:250. Acta Neuropathol Commun (2016) ncbi |
domestic rabbit polyclonal |
| In order to learn about potentiation of behavioral abnormalities, disturbing of iron pathways, and exacerbation of harmaline-induced tremor in mice due to loss of NCB5OR in the cerebellum, Cell Signaling Technology APP antibody (Cell signaling, 2452) was used in western blot on mouse samples (fig 1). Metab Brain Dis (2016) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell signaling, 8243) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4), in western blot on mouse samples at 1:4000 (fig 4) and in western blot on human samples at 1:4000 (fig 4). Nat Commun (2016) ncbi |
domestic rabbit monoclonal (D2A6H) |
| Cell Signaling Technology APP antibody (Cell signaling, 12467) was used in immunohistochemistry - paraffin section on human samples (fig 1). Acta Neuropathol Commun (2016) ncbi |
domestic rabbit monoclonal (D5Y9L) |
| Cell Signaling Technology APP antibody (Cell signaling, 12077) was used in immunohistochemistry - paraffin section on human samples (fig 1). Acta Neuropathol Commun (2016) ncbi |
domestic rabbit polyclonal |
| In order to study novelty-induced and brain-specific basal alternations in PI3K-Akt and MAPK/ERK signaling in a middle-aged A-betaPP/PS1 mouse model of Alzheimer's disease, Cell Signaling Technology APP antibody (CST, 2452) was used in western blot on mouse samples at 1:1000 (tbl 1). J Alzheimers Dis (2016) ncbi |
domestic rabbit polyclonal |
| In order to analyze chemogenetic modulation of neural activity by attenuation of beta-amyloid deposition and neurotoxicity, Cell Signaling Technology APP antibody (Cell Signaling, 2454) was used in immunohistochemistry on mouse samples (fig 1). J Neurosci (2016) ncbi |
domestic rabbit polyclonal |
| In order to study the coupling of cellular prion protein to intracellular signaling in Alzheimer's disease by metabotropic glutamate receptor 5, Cell Signaling Technology APP antibody (Cell Signalling, 2454) was used in immunohistochemistry on mouse samples at 1:250 (fig s9). Brain (2016) ncbi |
domestic rabbit monoclonal (D54D2) |
| Cell Signaling Technology APP antibody (Cell Signaling, 8243) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2015) ncbi |
domestic rabbit monoclonal (D54D2) |
| In order to determine the role of PICALM in Abeta transcytosis across the blood brain barrier, Cell Signaling Technology APP antibody (Cell Signaling Technology, 8243) was used in western blot on human samples at 1:200 (fig 7). Nat Neurosci (2015) ncbi |
domestic rabbit monoclonal (D54D2) |
| In order to assess the effect of carnosic acid on apoptosis induced by Abeta42 or Abeta43 in human neuroblastoma cells, Cell Signaling Technology APP antibody (Cell Signaling, #8243) was used in western blot on human samples at 1:1000. Neurosci Res (2015) ncbi |
domestic rabbit monoclonal (D2A6H) |
| In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, Cell Signaling Technology APP antibody (Cell Signaling, 12356BF) was used in ELISA on human samples and in western blot on human samples . Int J Alzheimers Dis (2014) ncbi |
Dako
mouse monoclonal (6F/3D) |
| Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry on human samples at 1:1000 (fig 1f). J Clin Med (2020) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 2a). Aging (Albany NY) (2020) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry on human samples at 1:50 (tbl 2). Neurology (2020) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako-Agilent, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a). Acta Neuropathol Commun (2019) ncbi |
mouse monoclonal (6F/3D) |
| In order to outline the protocols for antibodies used for immunohistochemical studies, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 and in immunohistochemistry on mouse samples (fig 16). J Toxicol Pathol (2017) ncbi |
mouse monoclonal (6F/3D) |
| In order to examine the mutation spectrum of the TANK-Binding Kinase 1 gene and its associated phenotypic spectrum in patients with FTD, ALS or FTD plus ALS, Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:400. Hum Mutat (2017) ncbi |
mouse monoclonal (6F/3D) |
| In order to test if ROCK1 governs the metabolism of amyloid precursor protein, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1a). Front Cell Neurosci (2016) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry - paraffin section on human samples . Am J Hum Genet (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to characterize an Alzheimer's disease model that utilizes Octodon degus, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 3). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (DakoCytomation, 6F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:400 (tbl 2). Alzheimers Res Ther (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to detail the neuropathological features of the anti-IgLON5 syndrome in order to diagnose patients, Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:400. Acta Neuropathol (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to characterize the cerebral cortex during the progression of Alzheimer disease pathology by visualizing subcellular changes in bridging integrator 1 protein expression, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 7). J Neuropathol Exp Neurol (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to study the attenuation of Alzheimer's pathology in mice due to kallikrein-8 inhibition, Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry on mouse samples at 1:100 (fig 4). Alzheimers Dement (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to assess the impairment in synaptic plasticity and learning due to amyloid-beta dimers in the absence of plaque pathology, Dako APP antibody (Dako, M0872) was used in immunohistochemistry on mouse samples at 1:100 (fig 2). Brain (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to present data from the first donated Lothian Birth Cohort of 1936 and compare it with other aged and diseased samples, Dako APP antibody (Dako, M087201-2) was used in immunohistochemistry - paraffin section on human samples at 1:100. Acta Neuropathol Commun (2015) ncbi |
mouse monoclonal (6F/3D) |
| In order to characterize the neuropathologic evaluation of Alzheimer's disease by multisite assessment of NIA-AA guidelines, Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry on human samples (tbl 1). Alzheimers Dement (2016) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry on human samples at 1:50 (fig 2). Neuropathology (2016) ncbi |
mouse monoclonal (6F/3D) |
| In order to investigate how microglia and iron contribute to Alzheimer's disease, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2). Neurobiol Aging (2015) ncbi |
mouse monoclonal (6F/3D) |
| In order to report the neuropathologic autopsy findings of a man with the rare Tyr69His transthyretin gene variant, Dako APP antibody (Dako, M0872) was used in immunohistochemistry on human samples at 1:400 (fig s1). Acta Neuropathol Commun (2015) ncbi |
mouse monoclonal (6F/3D) |
| In order to study neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease in mice, Dako APP antibody (Dako, 6 F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Neuropathol Exp Neurol (2015) ncbi |
mouse monoclonal (6F/3D) |
| In order to evaluate the role of DNA content in Lewy body diseases, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:500. Neurobiol Aging (2015) ncbi |
mouse monoclonal (6F/3D) |
| In order to investigate the abnormalites in hippocampal energy metabolism in the pathogenesis of Alzheimer disease, Dako APP antibody (DakoCytomation, 6F/3D) was used in immunohistochemistry - free floating section on mouse samples at 1:100. Biochim Biophys Acta (2014) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, M0872) was used in immunohistochemistry on human samples at 1:100. Neurobiol Aging (2014) ncbi |
mouse monoclonal (6F/3D) |
| Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:200. Glia (2013) ncbi |
mouse monoclonal (6F/3D) | Dako APP antibody (DAKO, M0872) was used . Exp Neurol (2009) ncbi | |
mouse monoclonal (6F/3D) |
| Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry - free floating section on human samples at 1:50. Brain Res (2001) ncbi |
Alpha Diagnostics
domestic rabbit |
| Alpha Diagnostics APP antibody (Alpha Diagnostic International, BAM421-A) was used in immunohistochemistry - paraffin section on rat samples at 1:200. Fluids Barriers CNS (2015) ncbi |
domestic rabbit |
| Alpha Diagnostics APP antibody (Alpha Diagnostic International, BAM401-A) was used in immunohistochemistry - paraffin section on rat samples at 1:100. Fluids Barriers CNS (2015) ncbi |
MilliporeSigma
domestic rabbit polyclonal |
| MilliporeSigma APP antibody (Sigma, A3356) was used in western blot on mouse samples . Cell Death Discov (2020) ncbi |
mouse monoclonal (BAM-10) |
| MilliporeSigma APP antibody (Sigma-Aldrich, A5213) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 4a). J Neuroinflammation (2020) ncbi |
mouse monoclonal (BAM-10) |
| MilliporeSigma APP antibody (Sigma, A5213) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Int J Mol Sci (2017) ncbi |
mouse monoclonal (BAM-10) |
| MilliporeSigma APP antibody (Sigma, A5213) was used in immunohistochemistry on mouse samples (fig 4). Int J Mol Med (2017) ncbi |
mouse monoclonal (NAB 228) |
| MilliporeSigma APP antibody (Sigma, A8354) was used in ELISA on human samples (fig 2,4). Biosens Bioelectron (2015) ncbi |
mouse monoclonal (NAB 228) |
| MilliporeSigma APP antibody (Sigma-Aldrich, A8354) was used in ELISA on mouse samples (fig s1). PLoS ONE (2014) ncbi |
mouse monoclonal (BAM-10) |
| MilliporeSigma APP antibody (Sigma-Aldrich, A3981) was used in ELISA on mouse samples (fig s1). PLoS ONE (2014) ncbi |
mouse monoclonal (NAB 228) |
| MilliporeSigma APP antibody (Sigma-Aldrich, A8354) was used in western blot on human samples (fig 7c). Mol Cell Neurosci (2014) ncbi |
Leica Biosystems
(6F/3D) |
| Leica Biosystems APP antibody (Novocastra, 6F-3D) was used in immunohistochemistry on human samples at 1:200 (fig 1). Acta Neuropathol Commun (2021) ncbi |
(6F/3D) |
| In order to analyze autopsied corpses and reveal that progressive supranuclear palsy may be more common than previously thought, Leica Biosystems APP antibody (Novocastra Vector Labs, 6F/3D) was used in immunohistochemistry on human samples at 1:50 (tbl 1). Acta Neuropathol (2017) ncbi |
(6F/3D) |
| In order to examine postmortem brain tissues from five institutionalized patients with schizophrenia and history of surgical leucotomy with subsequent survival of at least another 40 years, Leica Biosystems APP antibody (Leica Biosystems, 6F/3D) was used in western blot on human samples (fig 5). Acta Neuropathol (2017) ncbi |
Biosensis
mouse monoclonal |
| Biosensis APP antibody (Biosensis, M-1586-100) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 3). Front Neurosci (2016) ncbi |
mouse monoclonal |
| In order to investigate the relationship between beta-amyloid plaques and microglia, Biosensis APP antibody (Biosensis, M-1586-100) was used in immunohistochemistry on mouse samples (fig s2). Nat Commun (2015) ncbi |
Articles Reviewed
- Bradshaw D, Knutsen A, Korotcov A, Sullivan G, Radomski K, Dardzinski B, et al. Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures. Acta Neuropathol Commun. 2021;9:89 pubmed publisher
- Meilandt W, Ngu H, Gogineni A, Lalehzadeh G, Lee S, Srinivasan K, et al. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model. J Neurosci. 2020;40:1956-1974 pubmed publisher
- Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed publisher
- Thygesen C, Ilkjær L, Kempf S, Hemdrup A, von Linstow C, Babcock A, et al. Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease. Front Cell Neurosci. 2018;12:397 pubmed publisher
- Poulsen E, Iannuzzi F, Rasmussen H, Maier T, Enghild J, Jørgensen A, et al. An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients. Front Mol Neurosci. 2017;10:59 pubmed publisher
- Vienken H, Mabrouki N, Grabau K, Claas R, Rudowski A, Schömel N, et al. Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage. Sci Rep. 2017;7:43575 pubmed publisher
- Stachowicz A, Olszanecki R, Suski M, Głombik K, Basta Kaim A, Adamek D, et al. Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2). Int J Mol Sci. 2017;18: pubmed publisher
- Del Turco D, Paul M, Schlaudraff J, Hick M, Endres K, Müller U, et al. Region-Specific Differences in Amyloid Precursor Protein Expression in the Mouse Hippocampus. Front Mol Neurosci. 2016;9:134 pubmed
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