This is a Validated Antibody Database (VAD) review about human Notch1, based on 147 published articles (read how Labome selects the articles), using Notch1 antibody in all methods. It is aimed to help Labome visitors find the most suited Notch1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Notch1 synonym: AOS5; AOVD1; TAN1; hN1

Knockout validation
Abcam
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 4
In order to assess the effect of Notch1 inactivation in oroesophageal epithelium, Abcam Notch1 antibody (Abcam, EP1238Y) was used in immunohistochemistry knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 4). Biochem Biophys Res Commun (2016) ncbi
Abcam
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3a
Abcam Notch1 antibody (Abcam, ab52627) was used in immunohistochemistry knockout validation on mouse samples (fig 3a). PLoS ONE (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6F11)
  • western blot knockout validation; human; loading ...; fig 1-s1f
In order to analyze EOGT functions in Notch signaling-dependent retinal angiogenesis, Cell Signaling Technology Notch1 antibody (Cell signaling, D6F11) was used in western blot knockout validation on human samples (fig 1-s1f). elife (2017) ncbi
Abcam
mouse monoclonal (mN1A)
  • western blot; human; loading ...; fig 3c
Abcam Notch1 antibody (Abcam, 128076) was used in western blot on human samples (fig 3c). Cell Death Discov (2020) ncbi
domestic rabbit monoclonal
  • immunohistochemistry; human; loading ...; fig 3j
  • western blot; human; 1:1000; loading ...; fig 3c
Abcam Notch1 antibody (Abcam, ab194123) was used in immunohistochemistry on human samples (fig 3j) and in western blot on human samples at 1:1000 (fig 3c). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:600; loading ...; fig 3c
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on human samples at 1:600 (fig 3c). Cancer Sci (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1a
  • western blot; human; loading ...; fig s2c, s2d, s2e, s2f
Abcam Notch1 antibody (Abcam, ab8925) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1a) and in western blot on human samples (fig s2c, s2d, s2e, s2f). Mol Cancer (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5e
Abcam Notch1 antibody (Abcam, ab8925) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5e). Stem Cells Transl Med (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4g
  • western blot; human; loading ...; fig 4a
Abcam Notch1 antibody (Abcam, ab83232) was used in immunocytochemistry on human samples (fig 4g) and in western blot on human samples (fig 4a). Theranostics (2019) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; loading ...; fig 9b
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on human samples (fig 9b). Cancer Cell Int (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Abcam Notch1 antibody (Abcam, ab83232) was used in western blot on human samples (fig 5a). Cancer Cell Int (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5e
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on human samples at 1:1000 (fig 5e). Biosci Rep (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; zebrafish ; fig s7c
Abcam Notch1 antibody (Abcam, ab8387) was used in immunocytochemistry on zebrafish samples (fig s7c). Cell (2019) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; mouse; 1:1000; loading ...; fig 5o
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on mouse samples at 1:1000 (fig 5o). Science (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:75; loading ...; fig 4b
Abcam Notch1 antibody (Abcam, ab27526) was used in western blot on human samples at 1:75 (fig 4b). Biosci Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4o
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on mouse samples at 1:500 (fig 4o). Genes Dev (2017) ncbi
domestic rabbit polyclonal
  • other; mouse; loading ...; fig 6f
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5c
Abcam Notch1 antibody (Abcam, ab8925) was used in other on mouse samples (fig 6f) and in immunohistochemistry - paraffin section on mouse samples (fig 5c). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:100; loading ...; fig 5a
Abcam Notch1 antibody (Abcam, ab52301) was used in immunohistochemistry on rat samples at 1:100 (fig 5a). PLoS ONE (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 7a
In order to report that hepatocytes rapidly upregulate NF- kB and Smad2/3 activity, and repress Notch signaling, Abcam Notch1 antibody (Abcam, ab8925) was used in immunocytochemistry on human samples at 1:200 (fig 7a). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2c
In order to research the role of cargo protein MAP17 in cancer stem cells, Abcam Notch1 antibody (Abcam, ab8925) was used in immunocytochemistry on human samples (fig 2a) and in western blot on human samples (fig 2c). Clin Cancer Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 7e
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on mouse samples at 1:1000 (fig 7e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; mouse; 1:200; loading ...; fig 3c
Abcam Notch1 antibody (Abcam, EP1238Y) was used in western blot on mouse samples at 1:200 (fig 3c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 4a
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on rat samples (fig 4a). Am J Transl Res (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:25; loading ...; fig s1c
  • western blot; mouse; loading ...; fig 1a
  • western blot; human; loading ...; fig 1k
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Abcam Notch1 antibody (Abcam, ab52301) was used in immunohistochemistry on mouse samples at 1:25 (fig s1c), in western blot on mouse samples (fig 1a) and in western blot on human samples (fig 1k). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6b
  • immunocytochemistry; human; fig 8a
In order to use knockout mice to determine the role of a2V in mammary gland development, Abcam Notch1 antibody (Abcam, ab52627) was used in immunohistochemistry - frozen section on mouse samples (fig 6b) and in immunocytochemistry on human samples (fig 8a). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; loading ...; fig s2
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on human samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:1000; fig 5
Abcam Notch1 antibody (Abcam, ab8925) was used in immunohistochemistry on rat samples at 1:1000 (fig 5). Alzheimers Res Ther (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1h
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 4a
In order to demonstrate that mice with adipocyte-specific activation of Notch signaling develop liposarcomas with complete penetrance, Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on mouse samples (fig 1h) and in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 4a). J Exp Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; fig 1
Abcam Notch1 antibody (Abcam, ab8925) was used in immunohistochemistry on mouse samples at 1:200 (fig 1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:100; fig 1g
In order to study how transcriptional regulation and Skp2-mediated degradation of p27Kip1 activates stem cell properties of muller glia through notch signaling, Abcam Notch1 antibody (Abcam, ab27526) was used in immunocytochemistry on rat samples at 1:100 (fig 1g). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:100; fig 1g
  • western blot; rat; 1:500; fig 4c
In order to study how transcriptional regulation and Skp2-mediated degradation of p27Kip1 activates stem cell properties of muller glia through notch signaling, Abcam Notch1 antibody (Abcam, ab8925) was used in immunocytochemistry on rat samples at 1:100 (fig 1g) and in western blot on rat samples at 1:500 (fig 4c). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 6
  • western blot; human; fig 6
Abcam Notch1 antibody (Abcam, Ab83232) was used in immunohistochemistry - paraffin section on human samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; fig 4
  • western blot; mouse; fig 6
In order to analyze mediation of pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling due to the cyclic AMP response element binding protein, Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on human samples (fig 4) and in western blot on mouse samples (fig 6). EBioMedicine (2015) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 1
Abcam Notch1 antibody (Abcam, ab8925) was used in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 1
Abcam Notch1 antibody (Abcam, ab27526) was used in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (A6)
  • immunohistochemistry; mouse; 1:25; fig s11
  • proximity ligation assay; human; 1:50; fig 5
Abcam Notch1 antibody (Abcam, ab44986) was used in immunohistochemistry on mouse samples at 1:25 (fig s11) and in proximity ligation assay on human samples at 1:50 (fig 5). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 8
  • immunocytochemistry; human; 1:100; fig 1
  • western blot; human; 1:250; fig 1
Abcam Notch1 antibody (Abcam, ab8925) was used in immunohistochemistry on mouse samples at 1:100 (fig 8), in immunocytochemistry on human samples at 1:100 (fig 1) and in western blot on human samples at 1:250 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 4
In order to assess the effect of Notch1 inactivation in oroesophageal epithelium, Abcam Notch1 antibody (Abcam, EP1238Y) was used in immunohistochemistry knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 4). Biochem Biophys Res Commun (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; 1:1000; loading ...; fig 2b
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on human samples at 1:1000 (fig 2b). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
Abcam Notch1 antibody (Abcam, ab52627) was used in immunohistochemistry - paraffin section on human samples (fig 3a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3a
Abcam Notch1 antibody (Abcam, ab52627) was used in immunohistochemistry knockout validation on mouse samples (fig 3a). PLoS ONE (2015) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to elucidate mechanisms that regulate T cell glycolytic metabolism, Abcam Notch1 antibody (Abcam, ab52301) was used in western blot on human samples at 1:1000 (fig 3). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunocytochemistry; human; 5.0 ug/ml
In order to investigate the role of Notch signaling in human basal cell differentiation, Abcam Notch1 antibody (Abcam, ab52627) was used in immunocytochemistry on human samples at 5.0 ug/ml. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; 1:5000
In order to examine Notch localization and activation in non-small cell lung cancer, Abcam Notch1 antibody (Abcam, EP1238Y) was used in western blot on human samples at 1:5000. J Hematol Oncol (2015) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; human; loading ...; fig 6a
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on human samples (fig 6a). Int J Mol Med (2015) ncbi
mouse monoclonal (A6)
  • immunocytochemistry; human; 1:30
Abcam Notch1 antibody (Abcam, ab44986) was used in immunocytochemistry on human samples at 1:30. Am J Physiol Heart Circ Physiol (2014) ncbi
mouse monoclonal (A6)
  • immunohistochemistry - paraffin section; human; 1:200
Abcam Notch1 antibody (Abcam, ab44986) was used in immunohistochemistry - paraffin section on human samples at 1:200. Clin Chim Acta (2014) ncbi
domestic rabbit monoclonal (EP1238Y)
  • western blot; mouse
Abcam Notch1 antibody (Abcam, ab52627) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3c
Abcam Notch1 antibody (Abcam, EP1238Y) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3c). J Neurooncol (2014) ncbi
domestic rabbit monoclonal (EP1238Y)
  • immunohistochemistry - paraffin section; mouse; 1:50
Abcam Notch1 antibody (Abcam, Ab52627) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. PLoS ONE (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (mN1A)
  • flow cytometry; human; loading ...; fig 2l
Santa Cruz Biotechnology Notch1 antibody (Santa, sc32745) was used in flow cytometry on human samples (fig 2l). Br J Cancer (2019) ncbi
mouse monoclonal (A-8)
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz, sc-376403) was used in western blot on human samples at 1:1000 (fig 4a). Apoptosis (2017) ncbi
mouse monoclonal (C-10)
  • western blot; mouse; 1:1000; fig 7b
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz, sc-373891) was used in western blot on mouse samples at 1:1000 (fig 7b), in immunocytochemistry on human samples (fig 4b) and in western blot on human samples at 1:1000 (fig 3b). Oncol Lett (2016) ncbi
mouse monoclonal (E-4)
  • western blot; human; 1:1500; fig 4
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz Biotechnology, sc-373944) was used in western blot on human samples at 1:1500 (fig 4). Mol Med Rep (2016) ncbi
mouse monoclonal (C-10)
  • western blot; human; loading ...; fig 3c
Santa Cruz Biotechnology Notch1 antibody (SantaCruz, sc-373891) was used in western blot on human samples (fig 3c). Mol Med Rep (2015) ncbi
mouse monoclonal (mN1A)
  • western blot; human; fig 1b
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz, sc-32745) was used in western blot on human samples (fig 1b). Leukemia (2015) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry - paraffin section; mouse; 1:50
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz Biotechnology, sc-373891) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. Int J Cancer (2014) ncbi
mouse monoclonal (mN1A)
  • western blot; mouse; 1:500
Santa Cruz Biotechnology Notch1 antibody (Santa Cruz Biotechnology, sc-32745) was used in western blot on mouse samples at 1:500. Mol Neurobiol (2014) ncbi
Invitrogen
mouse monoclonal (MHN1-519)
  • flow cytometry; human; 1:50; loading ...; fig 2a
In order to elucidate the role of NOTCH1 in oncogene-induced senescence, Invitrogen Notch1 antibody (eBioscience, 17-9889) was used in flow cytometry on human samples at 1:50 (fig 2a). Nat Cell Biol (2016) ncbi
mouse monoclonal (A6)
  • immunohistochemistry; human; 1:500; fig 1
In order to discuss how injuries to the limbus affects stem cells, Invitrogen Notch1 antibody (Thermo Scientific, MS-1339) was used in immunohistochemistry on human samples at 1:500 (fig 1). Stem Cell Res Ther (2016) ncbi
mouse monoclonal (MHN1-519)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, Invitrogen Notch1 antibody (e- Bioscienc e, 17-9889-42) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (mN1A)
  • immunoprecipitation; human
In order to elucidate how Notch signaling contributes to T cell acute lymphoblastic leukemia using mice, Invitrogen Notch1 antibody (eBioscience, mN1A) was used in immunoprecipitation on human samples . PLoS ONE (2013) ncbi
mouse monoclonal (A6)
  • blocking or activating experiments; mouse
In order to report that Notch1 forms homodimers via its EGF motifs, Invitrogen Notch1 antibody (Neomakers, A6) was used in blocking or activating experiments on mouse samples . Exp Cell Res (2005) ncbi
MilliporeSigma
mouse monoclonal (3E12)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
In order to explore the impact of Notch1 signaling on the development of clear cell renal cell carcinoma, MilliporeSigma Notch1 antibody (Sigma, 3E12) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Sci Rep (2016) ncbi
mouse monoclonal (mN1A)
  • western blot; human
MilliporeSigma Notch1 antibody (Sigma-Aldrich, N6786) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (mN1A)
  • immunohistochemistry - paraffin section; mouse; 1:50
MilliporeSigma Notch1 antibody (Cell Signaling, N6786) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. Int J Cancer (2014) ncbi
R&D Systems
domestic sheep polyclonal
  • flow cytometry; human; 1:50; loading ...; fig 2b
  • western blot; human; 1:250; loading ...
In order to analyze EOGT functions in Notch signaling-dependent retinal angiogenesis, R&D Systems Notch1 antibody (R and D Systems, AF5267) was used in flow cytometry on human samples at 1:50 (fig 2b) and in western blot on human samples at 1:250. elife (2017) ncbi
domestic sheep polyclonal
  • flow cytometry; human; 10 ug/ml; loading ...; fig 1b
R&D Systems Notch1 antibody (R&D Systems, AF5267) was used in flow cytometry on human samples at 10 ug/ml (fig 1b). Science (2017) ncbi
domestic sheep polyclonal
  • western blot; human; 1:200; fig 6
R&D Systems Notch1 antibody (R&D Systems, AF3647) was used in western blot on human samples at 1:200 (fig 6). Nat Commun (2016) ncbi
Novus Biologicals
mouse monoclonal (OTI3E12)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Novus Biologicals Notch1 antibody (Novus Biologicals, 3E12) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (mN1A)
  • western blot; mouse; fig 6
  • western blot; human; fig 4
In order to analyze mediation of pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling due to the cyclic AMP response element binding protein, Novus Biologicals Notch1 antibody (Novus Biologicals, NB100-78,486) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 4). EBioMedicine (2015) ncbi
BioLegend
mouse monoclonal (MHN1-519)
  • flow cytometry; human; loading ...; fig 2b
BioLegend Notch1 antibody (BioLegend, MHN1-519) was used in flow cytometry on human samples (fig 2b). Stem Cells Dev (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples at 1:1000 (fig 5c). Genome Biol (2020) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology Notch1 antibody (CST, 4147) was used in western blot on human samples at 1:1000 (fig 1a). elife (2020) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; mouse; 1:1000; loading ...; fig 3d2d, 3h
Cell Signaling Technology Notch1 antibody (CST, 3608) was used in western blot on mouse samples at 1:1000 (fig 3d2d, 3h). elife (2020) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:1000; loading ...; fig 3f, 3h
Cell Signaling Technology Notch1 antibody (CST, 4147) was used in western blot on mouse samples at 1:1000 (fig 3f, 3h). elife (2020) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; fig 1d
Cell Signaling Technology Notch1 antibody (cell signaling, 3608) was used in western blot on human samples (fig 1d). Oncogenesis (2020) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1c
Cell Signaling Technology Notch1 antibody (CST, 3608) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1c). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples (fig 4c). Sci Adv (2020) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig 4c). Sci Adv (2020) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1a). elife (2019) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; loading ...; fig s1a, s1b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples (fig s1a, s1b). Mol Cancer (2019) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3d
Cell Signaling Technology Notch1 antibody (CST, 4147) was used in immunohistochemistry on mouse samples at 1:100 (fig 3d). elife (2019) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380S) was used in western blot on human samples (fig 3b). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380T) was used in western blot on human samples (fig 2f). Cancer Cell Int (2019) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 1e
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig 1e). J Exp Med (2019) ncbi
domestic rabbit monoclonal (D1E11)
  • immunocytochemistry; human; 1:100; loading ...; fig 2i
  • immunohistochemistry; human; 1:200; loading ...; fig 8b
  • western blot; human; 1:1000; loading ...; fig 4h
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in immunocytochemistry on human samples at 1:100 (fig 2i), in immunohistochemistry on human samples at 1:200 (fig 8b) and in western blot on human samples at 1:1000 (fig 4h). Nat Neurosci (2019) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; 1:1000; fig 2c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples at 1:1000 (fig 2c). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - paraffin section; mouse; fig 5c
  • western blot; mouse; fig 5d
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in immunohistochemistry - paraffin section on mouse samples (fig 5c), in western blot on mouse samples (fig 5d) and in western blot on human samples (fig 6c). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5a
Cell Signaling Technology Notch1 antibody (Cell Signalling Technology, 4147) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 5a). elife (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig s5j
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig s5j). Cell (2018) ncbi
domestic rabbit monoclonal (C44H11)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3268) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on mouse samples at 1:1000 (fig 2a). J Exp Med (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig s3i
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig s3i). Cell (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:200; loading ...; fig 1a
Cell Signaling Technology Notch1 antibody (Cell Signaling, D3B8) was used in western blot on mouse samples at 1:200 (fig 1a). J Immunol (2018) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:1000; loading ...; fig s3a
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on human samples at 1:1000 (fig s3a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:3000; loading ...; fig 1b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on mouse samples at 1:3000 (fig 1b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; mouse; 1:500; fig 5b
Cell Signaling Technology Notch1 antibody (CST, D6F11) was used in western blot on mouse samples at 1:500 (fig 5b). Life Sci (2018) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology Notch1 antibody (Cell Signaling, D3B8) was used in western blot on human samples at 1:1000 (fig 1e). Nature (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147) was used in western blot on human samples (fig 3e). Cancer Res (2017) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; mouse; fig 2c
In order to study the effect of Notch signalling on small-cell lung cancer progression, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on mouse samples (fig 2c). Nature (2017) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; 1:1000; fig 2a
Cell Signaling Technology Notch1 antibody (CST, 3608) was used in western blot on human samples at 1:1000 (fig 2a). J Cell Sci (2017) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; rat; 1:1000; loading ...; fig 1c
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on rat samples at 1:1000 (fig 1c). World J Gastroenterol (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; loading ...
In order to analyze EOGT functions in Notch signaling-dependent retinal angiogenesis, Cell Signaling Technology Notch1 antibody (Cell signaling, 4147) was used in western blot on human samples at 1:1000. elife (2017) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot knockout validation; human; loading ...; fig 1-s1f
In order to analyze EOGT functions in Notch signaling-dependent retinal angiogenesis, Cell Signaling Technology Notch1 antibody (Cell signaling, D6F11) was used in western blot knockout validation on human samples (fig 1-s1f). elife (2017) ncbi
domestic rabbit monoclonal (C44H11)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Notch1 antibody (CST, 3268) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (D6F11)
  • immunocytochemistry; rat; 1:100; loading ...; fig 4d
  • immunohistochemistry; rat; 1:100; loading ...; fig 1d
  • western blot; rat; 1:500; loading ...; fig 1a
In order to determine if hypertonic saline induces Notch signaling to regulate the production of proinflammatory mediators, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in immunocytochemistry on rat samples at 1:100 (fig 4d), in immunohistochemistry on rat samples at 1:100 (fig 1d) and in western blot on rat samples at 1:500 (fig 1a). BMC Neurosci (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry; rat; 1:100; loading ...; fig 1e
  • western blot; rat; 1:300; loading ...; fig 1a
In order to determine if hypertonic saline induces Notch signaling to regulate the production of proinflammatory mediators, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in immunohistochemistry on rat samples at 1:100 (fig 1e) and in western blot on rat samples at 1:300 (fig 1a). BMC Neurosci (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 5c
In order to find a Cdk5-Foxo1-Bim pathway in cell death in tumorspheres, implicating Cdk5 as a target for tumor-initiating cells, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig 5c). Br J Cancer (2017) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; loading ...; fig 5c
In order to find a Cdk5-Foxo1-Bim pathway in cell death in tumorspheres, implicating Cdk5 as a target for tumor-initiating cells, Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples (fig 5c). Br J Cancer (2017) ncbi
domestic rabbit monoclonal (C44H11)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology Notch1 antibody (Cell Signaling, 3268) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; loading ...; fig 3g
Cell Signaling Technology Notch1 antibody (cell signalling, 4147) was used in western blot on human samples at 1:1000 (fig 3g). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; 1:1000; fig s11a
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 3608) was used in western blot on human samples at 1:1000 (fig s11a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:200; loading ...; fig 3c
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D3B8) was used in western blot on mouse samples at 1:200 (fig 3c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (C44H11)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 3268) was used in western blot on human samples . Cell Syst (2017) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; mouse; loading ...; fig 1b
In order to demonstrate that PTEN loss results in ADAM17 and NOTCH signaling in prostate cancer cells, Cell Signaling Technology Notch1 antibody (Cell signaling, D1E11) was used in western blot on mouse samples (fig 1b). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry; mouse; 1:250; loading ...; fig 3b
  • western blot; mouse; 1:2000; loading ...; fig 3a
  • western blot; human; 1:2000; loading ...; fig 4c
Cell Signaling Technology Notch1 antibody (Cell signaling, 3608) was used in immunohistochemistry on mouse samples at 1:250 (fig 3b), in western blot on mouse samples at 1:2000 (fig 3a) and in western blot on human samples at 1:2000 (fig 4c). Neoplasia (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 4f
In order to investigate the role of the RTA-JAG1-Notch pathway in Kaposi's sarcoma-associated herpesvirus reactivation, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147P) was used in western blot on human samples (fig 4f). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology Notch1 antibody (Cell Signaling, D3B8) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 3c). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3b
Cell Signaling Technology Notch1 antibody (Cell Signaling, D1E11) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 3b). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:500; fig 3
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples at 1:500 (fig 3). Oncol Lett (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig s3
Cell Signaling Technology Notch1 antibody (Cell Signaling, D3B8) was used in western blot on human samples (fig s3). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (C37C7)
  • immunohistochemistry - paraffin section; human; loading ...; fig s4
Cell Signaling Technology Notch1 antibody (Cell Signaling, C37C7) was used in immunohistochemistry - paraffin section on human samples (fig s4). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:800; loading ...; fig 1b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples at 1:800 (fig 1b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology Notch1 antibody (cell signalling, 4380) was used in western blot on human samples at 1:1000 (fig 3a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C44H11)
  • western blot; human; 1:1000; loading ...; fig s3
In order to research the role of ORP4L for T-cell acute lymphoblastic leukemia cell survival, Cell Signaling Technology Notch1 antibody (cell signalling, 3268) was used in western blot on human samples at 1:1000 (fig s3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig 1
Cell Signaling Technology Notch1 antibody (Cell signaling, 4147) was used in western blot on human samples (fig 1). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • immunocytochemistry; human; loading ...; fig e6a
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D1E11) was used in immunocytochemistry on human samples (fig e6a). Nature (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:500; loading ...; fig 2b
In order to elucidate the role of NOTCH1 in oncogene-induced senescence, Cell Signaling Technology Notch1 antibody (Cell signaling, 4147) was used in western blot on human samples at 1:500 (fig 2b). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:1000; loading ...; fig 2e
In order to elucidate the role of NOTCH1 in oncogene-induced senescence, Cell Signaling Technology Notch1 antibody (Cell signaling, 4380) was used in western blot on human samples at 1:1000 (fig 2e). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6a
In order to elucidate the role of NOTCH1 in oncogene-induced senescence, Cell Signaling Technology Notch1 antibody (Cell signaling, 3608) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 6a). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; fig 6d
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples (fig 6d). Biochem Pharmacol (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; fig 7d
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147S) was used in western blot on mouse samples (fig 7d). elife (2016) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Notch1 antibody (Cell Signaling Tech, D6F11) was used in western blot on human samples at 1:1000 (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology Notch1 antibody (Cell Signaling Tech, D3B8) was used in western blot on human samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in western blot on human samples at 1:1000 (fig 6). Stem Cell Reports (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; fig 4d
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples at 1:1000 (fig 4d). Int J Cancer (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • immunocytochemistry; rat; 1:200; loading ...; fig 3b
  • western blot; rat; 1:1000; loading ...; fig 3a
Cell Signaling Technology Notch1 antibody (CST, 3608) was used in immunocytochemistry on rat samples at 1:200 (fig 3b) and in western blot on rat samples at 1:1000 (fig 3a). Cell Cycle (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; fig s2
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on mouse samples (fig s2). Biol Open (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:1000; fig 5
In order to investigate inhibition of neural stem cell proliferation through Wnt/beta-catenin pathway by its GAP domain via Porf-2, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147p) was used in western blot on mouse samples at 1:1000 (fig 5). Front Cell Neurosci (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - frozen section; mouse; 1:100; fig 6
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Notch1 antibody (Cell signaling, 4147) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 6) and in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry; human; 1:100; fig 4
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147) was used in immunohistochemistry on human samples at 1:100 (fig 4). Nat Genet (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:500; fig 2, 3
In order to analyze altered amyloid beta 42 production in conjunction with conformational changes in transmembrane domain 4 of presenilin 1, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples at 1:500 (fig 2, 3). J Neurosci (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig 5
In order to characterize promotion of non-productive angiogenesis by inhibition of endothelial Cdk5 that reduces tumor growth, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig 1
Cell Signaling Technology Notch1 antibody (Cell Signaling Tech, 4147) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; fig 6
Cell Signaling Technology Notch1 antibody (Cell Signaling Tech, 3608) was used in western blot on human samples (fig 6). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; hamsters
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on hamsters samples . Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; rat; fig 2
In order to characterize the thyroid carcinoma-associated PAX8-PPARG fusion protein and genomic binding and regulation of gene expression, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 3608) was used in western blot on rat samples (fig 2). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on human samples (fig 5b). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • immunocytochemistry; human; loading ...; fig 5d
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in immunocytochemistry on human samples (fig 5d) and in western blot on human samples (fig 5b). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C44H11)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig S1
  • western blot; human; 1:2000; loading ...; fig 5A
In order to determine the role of INSM1 in lung cancer, Cell Signaling Technology Notch1 antibody (Cell signaling, C44H11) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig S1) and in western blot on human samples at 1:2000 (fig 5A). Am J Pathol (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; 1:1000; fig s7d
Cell Signaling Technology Notch1 antibody (Cell Signaling technologies, 4147) was used in western blot on mouse samples at 1:1000 (fig s7d). Nat Med (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:1000; fig 5a
In order to analyze protein kinase LRRK2, parkinson's disease associated, which modulates notch signaling via the endosomal pathway, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D3B8) was used in western blot on human samples at 1:1000 (fig 5a). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:1000; fig 5a
In order to analyze protein kinase LRRK2, parkinson's disease associated, which modulates notch signaling via the endosomal pathway, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology,, D6F11) was used in western blot on human samples at 1:1000 (fig 5a). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; fig 8
Cell Signaling Technology Notch1 antibody (Cell Signalling, 4147S) was used in western blot on human samples (fig 8). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - frozen section; mouse; 1:200; fig 3
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3). Development (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; mouse; fig 9a
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147) was used in western blot on mouse samples (fig 9a). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - paraffin section; human; 1:25
In order to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer, Cell Signaling Technology Notch1 antibody (Cell Signaling, 3608) was used in immunohistochemistry - paraffin section on human samples at 1:25. Oncotarget (2015) ncbi
domestic rabbit monoclonal (D1E11)
  • western blot; human; fig f4
  • western blot; mouse; fig f6
Cell Signaling Technology Notch1 antibody (cell signaling technology, 3608S) was used in western blot on human samples (fig f4) and in western blot on mouse samples (fig f6). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; 1:2000
In order to investigate the role of Notch signaling in human basal cell differentiation, Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on human samples at 1:2000. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; loading ...; fig s4
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples (fig s4). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human; 1:500
In order to examine Notch localization and activation in non-small cell lung cancer, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D3B8) was used in western blot on human samples at 1:500. J Hematol Oncol (2015) ncbi
domestic rabbit monoclonal (D3B8)
  • immunohistochemistry - frozen section; human; 1:100
  • western blot; human; 1:800
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in immunohistochemistry - frozen section on human samples at 1:100 and in western blot on human samples at 1:800. Oncotarget (2015) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology Inc., 4380) was used in western blot on human samples (fig 5a). Mol Carcinog (2015) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human; fig 1
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4380) was used in western blot on human samples (fig 1). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D1E11)
  • chromatin immunoprecipitation; mouse; fig 1
Cell Signaling Technology Notch1 antibody (Cell Signaling, D1E11) was used in chromatin immunoprecipitation on mouse samples (fig 1). J Immunol (2015) ncbi
domestic rabbit monoclonal (C44H11)
  • western blot; human; 1:1,000
Cell Signaling Technology Notch1 antibody (Cell Signaling, 3268s) was used in western blot on human samples at 1:1,000. Am J Physiol Heart Circ Physiol (2014) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4147) was used in western blot on human samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D6F11)
  • western blot; human
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4380) was used in western blot on human samples . PLoS ONE (2014) ncbi
rat monoclonal (5B5)
  • western blot; human
In order to examine the effects of kinase inhibtors that target the epidermal growth factor receptor in lung cancer, Cell Signaling Technology Notch1 antibody (Cell Signaling, 5B5) was used in western blot on human samples . Cancer Res (2014) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human
Cell Signaling Technology Notch1 antibody (Cell Signaling, 4147) was used in western blot on human samples . J Natl Cancer Inst (2014) ncbi
domestic rabbit monoclonal (D3B8)
  • chromatin immunoprecipitation; mouse
Cell Signaling Technology Notch1 antibody (Cell Signalling, 4147) was used in chromatin immunoprecipitation on mouse samples . Leukemia (2014) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - paraffin section; human
  • immunohistochemistry - paraffin section; rat
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D1E11) was used in immunohistochemistry - paraffin section on human samples and in immunohistochemistry - paraffin section on rat samples . Lab Invest (2013) ncbi
domestic rabbit monoclonal (C44H11)
  • western blot; human
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, C44H11) was used in western blot on human samples . Lab Invest (2013) ncbi
domestic rabbit monoclonal (D3B8)
  • western blot; human
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D3B8) was used in western blot on human samples . Lab Invest (2013) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry; human; 1:100
Cell Signaling Technology Notch1 antibody (Cell, 3608) was used in immunohistochemistry on human samples at 1:100. Neuro Oncol (2013) ncbi
domestic rabbit monoclonal (D6F11)
  • immunocytochemistry; pigs ; 1:200
  • western blot; pigs ; 1:1000
Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, 4380) was used in immunocytochemistry on pigs samples at 1:200 and in western blot on pigs samples at 1:1000. Cell Signal (2013) ncbi
domestic rabbit monoclonal (D1E11)
  • immunohistochemistry - paraffin section; human; 0.7 ug/ml
In order to study the role of Notch signaling in regulating IL-33 expression in quiescent endothelial cells, Cell Signaling Technology Notch1 antibody (Cell Signaling Technology, D1E11) was used in immunohistochemistry - paraffin section on human samples at 0.7 ug/ml. Am J Pathol (2012) ncbi
Developmental Studies Hybridoma Bank
rat monoclonal (bTAN 20)
  • western blot; human
Developmental Studies Hybridoma Bank Notch1 antibody (DSHB, bTAN20) was used in western blot on human samples . Int J Cancer (2018) ncbi
rat monoclonal (bTAN 20)
  • western blot; mouse; loading ...; fig 2b
Developmental Studies Hybridoma Bank Notch1 antibody (DSHB, bTAN 20) was used in western blot on mouse samples (fig 2b). Cell Death Dis (2016) ncbi
Articles Reviewed
  1. Eyler C, Matsunaga H, Hovestadt V, Vantine S, van Galen P, Bernstein B. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol. 2020;21:174 pubmed publisher
  2. Caolo V, Debant M, Endesh N, Futers T, Lichtenstein L, Bartoli F, et al. Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. elife. 2020;9: pubmed publisher
  3. Kuang Y, Golan O, Preusse K, Cain B, Christensen C, Salomone J, et al. Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism. elife. 2020;9: pubmed publisher
  4. Saini N, Sarin A. Nucleolar localization of the Notch4 intracellular domain underpins its regulation of the cellular response to genotoxic stressors. Cell Death Discov. 2020;6:7 pubmed publisher
  5. Chandrasekaran B, Dahiya N, Tyagi A, Kolluru V, Saran U, Baby B, et al. Chronic exposure to cadmium induces a malignant transformation of benign prostate epithelial cells. Oncogenesis. 2020;9:23 pubmed publisher
  6. Hu J, Yu J, Gan J, Song N, Shi L, Liu J, et al. Notch1/2/3/4 are prognostic biomarker and correlated with immune infiltrates in gastric cancer. Aging (Albany NY). 2020;12:2595-2609 pubmed publisher
  7. Dang N, Jiao J, Meng X, An Y, Han C, Huang S. Abnormal overexpression of G9a in melanoma cells promotes cancer progression via upregulation of the Notch1 signaling pathway. Aging (Albany NY). 2020;12:2393-2407 pubmed publisher
  8. Liu H, Mei F, Yang W, Wang H, Wong E, Cai J, et al. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Sci Adv. 2020;6:eaay3566 pubmed publisher
  9. Ding X, Hu H, Huang K, Wei R, Min J, Qi C, et al. Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma. Cancer Sci. 2020;111:489-501 pubmed publisher
  10. Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed publisher
  11. Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, et al. ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Mol Cancer. 2019;18:156 pubmed publisher
  12. Stupnikov M, Yang Y, Mori M, LU J, Cardoso W. Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. elife. 2019;8: pubmed publisher
  13. Duhachek Muggy S, Bhat K, Medina P, Cheng F, He L, Alli C, et al. Radiation Mitigation of the Intestinal Acute Radiation Injury in Mice by 1-[(4-Nitrophenyl)Sulfonyl]-4-Phenylpiperazine. Stem Cells Transl Med. 2019;: pubmed publisher
  14. Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, et al. Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis. Theranostics. 2019;9:4827-4840 pubmed publisher
  15. Capulli M, Hristova D, Valbret Z, Carys K, Arjan R, Maurizi A, et al. Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry. Br J Cancer. 2019;121:157-171 pubmed publisher
  16. He W, Tang J, Li W, Li Y, Mei Y, He L, et al. Mutual regulation of JAG2 and PRAF2 promotes migration and invasion of colorectal cancer cells uncoupled from epithelial-mesenchymal transition. Cancer Cell Int. 2019;19:160 pubmed publisher
  17. Chen P, Zhao D, Li J, Liang X, Li J, Chang A, et al. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma. Cancer Cell. 2019;35:868-884.e6 pubmed publisher
  18. Wu K, Zou J, Lin C, Jie Z. MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling. Biosci Rep. 2019;: pubmed publisher
  19. Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed publisher
  20. Xia P, Gütl D, Zheden V, Heisenberg C. Lateral Inhibition in Cell Specification Mediated by Mechanical Signals Modulating TAZ Activity. Cell. 2019;176:1379-1392.e14 pubmed publisher
  21. Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed publisher
  22. Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed publisher
  23. Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed publisher
  24. Li L, Guturi K, Gautreau B, Patel P, Saad A, Morii M, et al. Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis. J Clin Invest. 2018;128:4525-4542 pubmed publisher
  25. Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero Jimenez A, et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. elife. 2018;7: pubmed publisher
  26. Chakrabarti R, Celià Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, et al. Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science. 2018;360: pubmed publisher
  27. Pan B, Wu L, Pan L, Yang Y, Li H, Dai Y, et al. Up-regulation of microRNA-340 promotes osteosarcoma cell apoptosis while suppressing proliferation, migration, and invasion by inactivating the CTNNB1-mediated Notch signaling pathway. Biosci Rep. 2018;38: pubmed publisher
  28. Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. Cell. 2018;173:74-89.e20 pubmed publisher
  29. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  30. Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, et al. Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia. Int J Cancer. 2018;143:958-970 pubmed publisher
  31. Hu X, Das B, Hou H, He W, Yan R. BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions. J Exp Med. 2018;215:927-940 pubmed publisher
  32. Nandagopal N, Santat L, Lebon L, Sprinzak D, Bronner M, Elowitz M. Dynamic Ligand Discrimination in the Notch Signaling Pathway. Cell. 2018;172:869-880.e19 pubmed publisher
  33. Steinbuck M, Arakcheeva K, Winandy S. Novel TCR-Mediated Mechanisms of Notch Activation and Signaling. J Immunol. 2018;200:997-1007 pubmed publisher
  34. Bhardwaj A, Yang Y, Ueberheide B, Smith S. Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation. Nat Commun. 2017;8:2214 pubmed publisher
  35. Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed publisher
  36. Ma Q, Wang Y, Zhang T, Zuo W. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy. Life Sci. 2018;193:104-109 pubmed publisher
  37. Polacheck W, Kutys M, Yang J, Eyckmans J, Wu Y, Vasavada H, et al. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017;552:258-262 pubmed publisher
  38. Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
  39. Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  40. Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher
  41. Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed publisher
  42. Lian W, Zhang L, Yang L, Chen W. AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. Apoptosis. 2017;22:933-941 pubmed publisher
  43. Zhu X, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, et al. A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017;292:9409-9419 pubmed publisher
  44. Wang Y, Shen R, Han B, Li Z, Xiong L, Zhang F, et al. Notch signaling mediated by TGF-?/Smad pathway in concanavalin A-induced liver fibrosis in rats. World J Gastroenterol. 2017;23:2330-2336 pubmed publisher
  45. Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, et al. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. elife. 2017;6: pubmed publisher
  46. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  47. Zeng W, Han Y, Zhu G, Huang L, Deng Y, Wang Q, et al. Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia. BMC Neurosci. 2017;18:32 pubmed publisher
  48. Puhakka N, Bot A, Vuokila N, Dębski K, Lukasiuk K, Pitkanen A. Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury. PLoS ONE. 2017;12:e0172521 pubmed publisher
  49. Luca V, Kim B, Ge C, Kakuda S, Wu D, Roein Peikar M, et al. Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Science. 2017;355:1320-1324 pubmed publisher
  50. Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher
  51. Delhove J, Buckley S, Perocheau D, Karda R, Arbuthnot P, Henderson N, et al. Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice. Sci Rep. 2017;7:41874 pubmed publisher
  52. García Heredia J, Lucena Cacace A, Verdugo Sivianes E, Pérez M, Carnero A. The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB. Clin Cancer Res. 2017;23:3871-3883 pubmed publisher
  53. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  54. Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  55. Yue F, Bi P, Wang C, Shan T, Nie Y, Ratliff T, et al. Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun. 2017;8:14328 pubmed publisher
  56. Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002 pubmed publisher
  57. Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed publisher
  58. Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed publisher
  59. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  60. Revandkar A, Perciato M, Toso A, Alajati A, Chen J, Gerber H, et al. Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Nat Commun. 2016;7:13719 pubmed publisher
  61. Li F, Li Z, Jiang Z, Tian Y, Wang Z, Yi W, et al. Enhancement of early cardiac differentiation of dedifferentiated fat cells by dimethyloxalylglycine via notch signaling pathway. Am J Transl Res. 2016;8:4791-4801 pubmed
  62. Xiao Y, Yang X, Miao Y, He X, Wang M, Sha W. Inhibition of cell proliferation and tumor growth of colorectal cancer by inhibitors of Wnt and Notch signaling pathways. Oncol Lett. 2016;12:3695-3700 pubmed
  63. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  64. Pamarthy S, Mao L, Katara G, Fleetwood S, Kulshreshta A, Gilman Sachs A, et al. The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling. Cell Death Dis. 2016;7:e2443 pubmed publisher
  65. Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed publisher
  66. Li S, Hu H, He Z, Liang D, Sun R, Lan K. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016;12:e1005900 pubmed publisher
  67. Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  68. Greene L, Nathwani S, Zisterer D. Inhibition of ?-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5. Oncol Lett. 2016;12:2900-2905 pubmed
  69. Stoyanova T, Riedinger M, Lin S, Faltermeier C, Smith B, Zhang K, et al. Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:E6457-E6466 pubmed
  70. Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, et al. Targeting Notch signaling as a novel therapy for retinoblastoma. Oncotarget. 2016;7:70028-70044 pubmed publisher
  71. Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed publisher
  72. Zhang S, Wang P, Ren L, Hu C, Bi J. Protective effect of melatonin on soluble A?1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther. 2016;8:40 pubmed publisher
  73. Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed publisher
  74. Bi P, Yue F, Karki A, Castro B, Wirbisky S, Wang C, et al. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med. 2016;213:2019-37 pubmed publisher
  75. Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  76. Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
  77. Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
  78. Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed publisher
  79. Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed publisher
  80. Deskin B, Lasky J, Zhuang Y, Shan B. Requirement of HDAC6 for activation of Notch1 by TGF-?1. Sci Rep. 2016;6:31086 pubmed publisher
  81. Johansson E, Rönö B, Johansson M, Lindgren D, Möller C, Axelson H, et al. Simultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice. Sci Rep. 2016;6:30739 pubmed publisher
  82. Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, et al. MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network. Stem Cell Reports. 2016;7:236-48 pubmed publisher
  83. Fujiwara T, Zhou J, Ye S, Zhao H. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival. Cell Death Dis. 2016;7:e2300 pubmed publisher
  84. Phillips E, Lang V, Bohlen J, Bethke F, Puccio L, Tichy D, et al. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism. Int J Cancer. 2016;139:1776-87 pubmed publisher
  85. Zeng J, Jing Y, Shi R, Pan X, Lai F, Liu W, et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. Cell Cycle. 2016;15:1602-10 pubmed publisher
  86. Mathan J, Ismail S, McGhee J, McGhee C, Sherwin T. Sphere-forming cells from peripheral cornea demonstrate the ability to repopulate the ocular surface. Stem Cell Res Ther. 2016;7:81 pubmed publisher
  87. Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
  88. Carofino B, Ayanga B, Tracey L, Brooke Bisschop T, Justice M. PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL. Biol Open. 2016;5:645-53 pubmed publisher
  89. Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed publisher
  90. Huang G, Yang X, Chen K, Xing J, Guo L, Zhu L, et al. Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/?-Catenin Pathway by Its GAP Domain. Front Cell Neurosci. 2016;10:85 pubmed publisher
  91. Del Debbio C, Mir Q, Parameswaran S, Mathews S, Xia X, Zheng L, et al. Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1. PLoS ONE. 2016;11:e0152025 pubmed publisher
  92. Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
  93. Ye L, Qiu L, Zhang H, Chen H, Jiang C, Hong H, et al. Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation. Sci Rep. 2016;6:23188 pubmed publisher
  94. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  95. Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
  96. Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed publisher
  97. Liu B, Ma A, Zhang F, Wang Y, Li Z, Li Q, et al. MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis. Sci Rep. 2016;6:21534 pubmed publisher
  98. Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed publisher
  99. Drier Y, Cotton M, Williamson K, Gillespie S, Ryan R, Kluk M, et al. An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Nat Genet. 2016;48:265-72 pubmed publisher
  100. Tominaga A, Cai T, Takagi Niidome S, Iwatsubo T, Tomita T. Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production. J Neurosci. 2016;36:1362-72 pubmed publisher
  101. Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb J, et al. Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. Oncotarget. 2016;7:6088-104 pubmed publisher
  102. Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  103. Bolduc D, Montagna D, Gu Y, Selkoe D, Wolfe M. Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain. Proc Natl Acad Sci U S A. 2016;113:E509-18 pubmed publisher
  104. Mandasari M, Sawangarun W, Katsube K, Kayamori K, Yamaguchi A, Sakamoto K. A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis. Biochem Biophys Res Commun. 2016;469:761-7 pubmed publisher
  105. Wang Y, Hou H, Li M, Yang Y, Sun L. Anticancer effect of eupatilin on glioma cells through inhibition of the Notch-1 signaling pathway. Mol Med Rep. 2016;13:1141-6 pubmed publisher
  106. Chen X, Dong X, Gao H, Jiang Y, Jin Y, Chang Y, et al. Suppression of HSP27 increases the anti‑tumor effects of quercetin in human leukemia U937 cells. Mol Med Rep. 2016;13:689-96 pubmed publisher
  107. Denicolaï E, Tabouret E, Colin C, Metellus P, Nanni I, Boucard C, et al. Molecular heterogeneity of glioblastomas: does location matter?. Oncotarget. 2016;7:902-13 pubmed publisher
  108. Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher
  109. Shao H, Kong R, Ferrari M, Radtke F, Capobianco A, Liu Z. Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion. PLoS ONE. 2015;10:e0142815 pubmed publisher
  110. Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, et al. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol. 2016;17:95-103 pubmed publisher
  111. Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed publisher
  112. Fujino K, Motooka Y, Hassan W, Ali Abdalla M, Sato Y, Kudoh S, et al. Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer. Am J Pathol. 2015;185:3164-77 pubmed publisher
  113. Herranz D, Ambesi Impiombato A, Sudderth J, Sánchez Martín M, Belver L, Tosello V, et al. Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat Med. 2015;21:1182-9 pubmed publisher
  114. Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher
  115. Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLoS ONE. 2015;10:e0137614 pubmed publisher
  116. Liu Z, Brunskill E, Varnum Finney B, Zhang C, Zhang A, Jay P, et al. The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development. 2015;142:2452-63 pubmed publisher
  117. Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher
  118. Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  119. Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
  120. Gomi K, Arbelaez V, Crystal R, Walters M. Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. PLoS ONE. 2015;10:e0116507 pubmed publisher
  121. Sato M, Rodríguez Barrueco R, Yu J, Do C, Silva J, Gautier J. MYC is a critical target of FBXW7. Oncotarget. 2015;6:3292-305 pubmed
  122. Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski J, Ivy P, et al. Notch1 phenotype and clinical stage progression in non-small cell lung cancer. J Hematol Oncol. 2015;8:9 pubmed publisher
  123. Sun Z, Zhang C, Zou X, Jiang G, Xu Z, Li W, et al. Special AT-rich sequence-binding protein-1 participates in the maintenance of breast cancer stem cells through regulation of the Notch signaling pathway and expression of Snail1 and Twist1. Mol Med Rep. 2015;11:3235-542 pubmed publisher
  124. Lim K, Brandt W, Heth J, Muraszko K, Fan X, Bar E, et al. Lateral inhibition of Notch signaling in neoplastic cells. Oncotarget. 2015;6:1666-77 pubmed
  125. Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed publisher
  126. Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  127. Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed publisher
  128. Xie F, Cai W, Liu Y, Li Y, Du B, Feng L, et al. Vaccarin attenuates the human EA.hy926 endothelial cell oxidative stress injury through inhibition of Notch signaling. Int J Mol Med. 2015;35:135-42 pubmed publisher
  129. Ortega M, Bhatnagar H, Lin A, Wang L, Aster J, Sill H, et al. A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies. Leukemia. 2015;29:968-76 pubmed publisher
  130. Kakar S, Ratajczak M, Powell K, Moghadamfalahi M, Miller D, Batra S, et al. Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells. PLoS ONE. 2014;9:e107596 pubmed publisher
  131. Singla R, Wang J, Singla D. Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation. Am J Physiol Heart Circ Physiol. 2014;307:H1634-42 pubmed publisher
  132. So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed publisher
  133. Arasada R, Amann J, Rahman M, Huppert S, Carbone D. EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling. Cancer Res. 2014;74:5572-84 pubmed publisher
  134. Wang H, Huang X, Zhang J, Shao N, Chen L, Ma D, et al. The expression of VEGF and Dll4/Notch pathway molecules in ovarian cancer. Clin Chim Acta. 2014;436:243-8 pubmed publisher
  135. Aydin I, Melamed R, Adams S, Castillo Martin M, Demir A, Bryk D, et al. FBXW7 mutations in melanoma and a new therapeutic paradigm. J Natl Cancer Inst. 2014;106:dju107 pubmed publisher
  136. Kumar V, Palermo R, Talora C, Campese A, Checquolo S, Bellavia D, et al. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:2324-35 pubmed publisher
  137. Redmond E, Liu W, Hamm K, Hatch E, Cahill P, Morrow D. Perivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodeling. PLoS ONE. 2014;9:e84122 pubmed publisher
  138. Xiong H, Maraver A, Latkowski J, Henderson T, Schlessinger K, Ding Y, et al. Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells. PLoS ONE. 2013;8:e84841 pubmed publisher
  139. Gupta R, Sharma M, Suri V, Kakkar A, Singh M, Sarkar C. Study of chromosome 9q gain, Notch pathway regulators and Tenascin-C in ependymomas. J Neurooncol. 2014;116:267-74 pubmed publisher
  140. Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, et al. Obesity induced a leptin-Notch signaling axis in breast cancer. Int J Cancer. 2014;134:1605-16 pubmed publisher
  141. Murta D, Batista M, Silva E, Trindade A, Henrique D, Duarte A, et al. Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle. PLoS ONE. 2013;8:e72767 pubmed publisher
  142. Sha L, Wu X, Yao Y, Wen B, Feng J, Sha Z, et al. Notch signaling activation promotes seizure activity in temporal lobe epilepsy. Mol Neurobiol. 2014;49:633-44 pubmed publisher
  143. Yoshida R, Nagata M, Nakayama H, Niimori Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher
  144. El Hindy N, Keyvani K, Pagenstecher A, Dammann P, Sandalcioglu I, Sure U, et al. Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme. Neuro Oncol. 2013;15:1366-78 pubmed publisher
  145. Qin L, Xu J, Wu Z, Zhang Z, Li J, Wang C, et al. Notch1-mediated signaling regulates proliferation of porcine satellite cells (PSCs). Cell Signal. 2013;25:561-9 pubmed publisher
  146. Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Küchler A, WEISS M, et al. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012;181:1099-111 pubmed publisher
  147. Sakamoto K, Chao W, Katsube K, Yamaguchi A. Distinct roles of EGF repeats for the Notch signaling system. Exp Cell Res. 2005;302:281-91 pubmed